D-Dimer, platelets and C-reactive protein in patients with COVID-19: Correlations in deceased and surviving patients

Resumen

Introduction: COVID-19 is a disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) associated with activation of the inflammatory process. Objective: This study aims to determine D-Dimer, platelets, and C-reactive protein (CRP) in COVID-19 patients and controls and to determine these values in surviving and deceased COVID-19 patients. Method: Descriptive, retrospective, and cross-sectional research was conducted from March to June 2020. A total of 59 patients underwent SARS-CoV-2 testing and were diagnosed with COVID-19. They were classified into two groups according to their evolution (survivors: 49 and deceased: 10). A healthy control group (N=20) was also analyzed. Result: In general, during COVID-19, the values of D-Dimer and CRP were found to increase significantly compared to control individuals. The highest values were found in patients who died during the disease.