Obesity and depression: A molecular and epidemiological view of two comorbid disorders

Abstract

Currently, depression and obesity are chronic disorders considered public health problems because of their association with functional impairment, ominous healthcare costs, and increased morbidity and mortality rates worldwide. However, based on the high prevalence of both pathologies, a possible relationship between obesity and depression has been presumed and studied in recent years, demonstrated through observational epidemiological studies and meta-analyses, positioning them as commonly comorbid chronic diseases.