Chemotherapy-Induced Cardiotoxicity in Lung Cancer Patients: A Systematic Review of Case Reports

Abstract

Cardiotoxicity is one of the most relevant complications associated with the use of chemotherapeutic agents due to their adverse effects on a patient’s prognosis and quality of life. This review aimed to capture the clinical profile of patients with advanced lung cancer with chemotherapy, as well as to summarize the type, risk factors, incidence, management, and outcomes of chemotherapy-related cardiotoxicity. From systematic searching, we included ten articles. The mean age of all case reports was 60.1 ± 6.9 years, and 90% of cases were male. The majority (60%) of lung cancer reported in this review was non-small cell carcinoma (NSCC).