Inflammatory Profile in Chronic Hepatitis B Patients with and without Liver Cirrhosis: A Comparative Study of IFN-γ and IL-10 Levels
Perfil inflamatorio en pacientes con hepatitis B crónica con y sin cirrosis hepática: Un estudio comparativo de los niveles de IFN‑γ e IL‑10
Keywords:
Chronic hepatitis B, liver cirrhosis, IFN- γIL-10, cytokine profileAbstract
Introduction: Chronic hepatitis B (CHB) remains a major global health burden, often progressing to liver cirrhosis (LC) and hepatocellular carcinoma (HCC). The immune response, particularly the balance between pro-inflammatory cytokines like interferon-gamma (IFN-γ) and anti-inflammatory cytokines such as interleukin-10 (IL-10), plays a crucial role in disease progression. This study aimed to compare serum levels of IFN-γ and IL-10 in CHB patients with and without liver cirrhosis and to evaluate the IFN-γ/IL-10 ratio as a marker of immune balance.
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Published
2026-03-21
How to Cite
Rahmadhona, D., Purwanto, B., Hasan, I., & Aryati, A. (2026). Inflammatory Profile in Chronic Hepatitis B Patients with and without Liver Cirrhosis: A Comparative Study of IFN-γ and IL-10 Levels: Perfil inflamatorio en pacientes con hepatitis B crónica con y sin cirrosis hepática: Un estudio comparativo de los niveles de IFN‑γ e IL‑10. Gaceta Médica De Caracas, 134(1), 51–59. Retrieved from https://saber.ucv.ve/ojs/index.php/rev_gmc/article/view/32533
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ARTÍCULOS ORIGINALES
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Copyright (c) 2026 Gaceta Médica de Caracas
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
