Cut-off Point of Ki-67 Proliferation Marker in Differentiating Premalignant and Malignant Prostatic Lesions

Authors

  • Lidya Imelda Laksmi Department of Anatomical Pathology, Faculty of Medicine, Universitas Sumatera Utara, Indonesia http://orcid.org/0000-0002-2390-1499
  • Syafrudin Ilyas Department of Biology, Universitas Sumatera Utara, Indonesia
  • Nurjati Chairany Siregar Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Indonesia
  • Arlinda Sari Wahyunio Department of Public Health, Universitas Sumatera Utara, Indonesia http://orcid.org/0000-0002-5265-4685

Keywords:

Cut-Off point, Ki-67 immunohistochemistry, malignant, premalignant, prostate lesions

Abstract

Immunohistochemistry Ki-67 is a marker of cell proliferation. Using immunohistochemical markers can be helpful to determine and diagnose prostate intraepithelial neoplasia (PIN) and carcinoma prostate. There are many studies about Ki67 as a prognostic tool, a diagnostic tool, and a potential therapeutic target for cancer therapy, but there are no standard criteria to define the cut-off point for the value of Ki-67 in premalignant and malignant prostate lesions.

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Published

2022-06-02

How to Cite

Laksmi, L. I., Ilyas, S., Siregar, N. C., & Wahyunio, A. S. (2022). Cut-off Point of Ki-67 Proliferation Marker in Differentiating Premalignant and Malignant Prostatic Lesions. Gaceta Médica De Caracas, 130(1 S), S60-S63. Retrieved from https://saber.ucv.ve/ojs/index.php/rev_gmc/article/view/23884

Issue

Vol. 130 No. 1 S (2022)

Section

ARTÍCULOS ORIGINALES

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