Ghrelin and C-peptide as biomarkers for hypercholesterolemia
Keywords:
Ghrelin, C-peptide, cholesterol, inflammation, C reactive protein, biomarkers, hypercholesterolemia.Abstract
Inflammation and hypercholesterolemia have been reported as risk factors involved in the pathogenesis of cardiovascular diseases. Ghrelin and its receptors are present in the myocardium and vasculature, were they exert cardio-protector and anti-inflammatory functions. C-peptide is a product of proinsulin that plays a physiological role in different types of cells and has pro and anti-inflammatory properties.
La inflamación y la hipercolesterolemia son considerados factores de riesgo involucrados en la patogénesis de las enfermedades cardiovasculares. La grelina y sus receptores están presentes en el miocardio y la vasculatura, donde ejercen funciones cardioprotectoras y antiinflamatorias. El péptido C es un producto de la proinsulina que juega un papel fisiológico en diferentes tipos de células y tiene propiedades pro y antiinflamatorias.
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