Architecture and operation of a neuronal circuit that modulates pain

Abstract

The present article is a narrative review that describes the functional characteristics of the neurons that constitute a system whose task is to facilitate or diminish the defensive reflexes and the sensation of pain elicited by real or potential damage to one of our tissues. These neurons are located in the medulla oblongata and are known as on-cells and off-cells.

El presente artículo es una revisión narrativa que describe las características funcionales de las neuronas que constituyen un sistema cuya tarea es facilitar o mitigar los reflejos defensivos y la sensación de dolor generados por un daño real o potencial a alguno de nuestros tejidos.