Invasive pulmonary aspergillosis in a pediatric patient

Abstract

The growing emergence of infectious diseases and increasing the number of individuals that have affected their immune competence has become a challenge. Furthermore, considering the genus Aspergillus, as an etiologic agent of infection, which causes significant morbidity and mortality in immunocompromised patients. We present a case of a female preschool 3 years and 8 months with a history of mature teratoma fetiforme, who after 6 months of excision, computed tomography (CT) scan control is performed where central bronchiectasis are evident with tubular opacities and saculares bronchial distribution, located mainly in the upper lobe of left chest, decreased left lung volume with incipient displacement of the heart and medistino left and low left pleural effusion, physical examination no alterations to income, so you enter with diagnosis of granulomatous disease study. antigen detection galactomannan reporting positive in two determinations so the diagnosis of invasive pulmonary aspergillosis rethinks meets voriconazole for 21 days, with significant improvement of lung lesions in chest CT scan, graduating with itraconazole therapy is performed to meet for 6 weeks. The early initiation of treatment is a fundamental prognostic factor of invasive aspergillosis, constituting the first line in voriconazole.