Evaluation of some physiological parameters for obese women suffering from pregnant disturbance in Basrah governorate, Iraq-Case Study

Abstract

Background: Obesity is a public health problem spreading markedly since 1980 till now, which has been increased for more than threefold. The World Health Organization (WHO) estimated that more than 700 million adults are obese, while 2.3 billion are overweight worldwide and nearly 4.3 million adults die every year from obesity and overweight health disturbance. This phenomenon coincided with an increase in infertility women.

Aim of study: evaluation the most common disorders in infertile obese women and compare them with the group of fertile obese women by testing some physiological parameters.

Subjects and methods: The study was conducted on patients attending to the gynecological consultations in Ibn Ghazwan maternity and children hospital and infertility center in Basrah governorate from August 2020 to February 2021. The study was included a random sample of 64 infertile women, obesity or overweight suffering from Endometriosis and polycystic ovarian syndrome in addition to 22 women volunteer who are fertile obese or overweight as control group.

Results: Statistical results for endometriosis subjects showed significant reduction in the concentration of Testosterone, LH and AMH hormones while the concentration of estrogen, leptin hormones, TNF-alpha and MDA were significantly higher compared with control group, while there was no significant difference for progesterone hormone concentration. Furthermore, the results of PCOS patients showed a significant rise in concentration of testosterone, LH, AMH, leptin hormones, TNF-alpha and MDA while the concentration of estrogen, progesterone and FSH hormones were significantly reduced.