Comparison of serum levels of thyroidstimulating hormone in preeclampsia and non-preeclampsia pregnant women referring to Karaj Kamali Hospital in 2018

Resumen

Introduction: As there is no reliable criterion for early diagnosisof preeclampsia up to present date, this study wasconducted to compare the serum levels of thyroid-stimulatinghormone in preeclampsia and non-preeclampsiapregnant women and the use of thyroid-stimulating hormone(TSH) as a predictive factor in preeclampsia.Method: In this case-control study, 45 non-preeclampsiapregnant women and 45 preeclampsia pregnant womenin the third trimester of pregnancy referred to Kamali Hospitalof Karaj were examined. A skilled person took 10 ccof venous blood of the subjects and the mean serum TSHlevels of both groups were compared by using SPSS, version22, software.Results: The mean serum TSH level was 2.55 ± 1.13 and3.08 ± 1.23, respectively, in non-preeclampsia pregnantwomen and preeclampsia pregnant women, the relationshipwas statistically significant (P =0.013). Besides, theprevalence of preterm delivery in preeclampsia pregnantwomen was higher than that in non-preeclampsia pregnantwomen (P = .000). The mean weight of neonatesin preeclampsia pregnant women was lower than that innon- preeclampsia pregnant women (P = .000).Conclusion: This study revealed that measuring serumTSH levels in the third trimester of pregnancy could be apredictor of preeclampsia.