Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione

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Título :	Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione
Autor :	Lobo, Gricela Charris, Katiuska Capparely, Mario Briceño, Alexander Ángel, Jorge Charris, Jaime Zuleta, Elimar
Palabras clave :	indeno[1,2-b]indole ninhydrin crystal structure regiospecific
Fecha de publicación :	18-abr-2011
Editorial :	JOURNAL OF CHEMICAL RESEARCH
Resumen :	A highly regiospecific synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-7,7-dimethyl-4b,9bdihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b]indole-9,10-dione is reported. It was tested in vitroagainst six human tumour cell lines and two nontumourogenic cell lines. Their in vitroactivity against Mycobacterium tuberculosisis also reported. In general, it was found to possess a marginal activity.
URI :	http://hdl.handle.net/10872/8220
ISSN :	1747-5198
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SYNTHESIS AND CRYSTAL STRUCTURE OF (4b,9b)-5-(2,4-DIMETHOXYPHENYL)-4b,9b-7,7-DIMETHYLDIHYDRO-4B,5,6,7,8,9B-HEXAHYDROINDENOL[1,2-B]INDOLE-9,10-DIONE.PDF		132.92 kB	Adobe PDF	Visualizar/Abrir

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