Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione | Saber UCV

Please use this identifier to cite or link to this item: https://saber.ucv.ve/handle/10872/8220

Title:	Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione
Authors:	Lobo, Gricela Charris, Katiuska Capparely, Mario Briceño, Alexander Ángel, Jorge Charris, Jaime Zuleta, Elimar
Keywords:	indeno[1,2-b]indole ninhydrin crystal structure regiospecific
Issue Date:	18-Apr-2011
Publisher:	JOURNAL OF CHEMICAL RESEARCH
Abstract:	A highly regiospecific synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-7,7-dimethyl-4b,9bdihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b]indole-9,10-dione is reported. It was tested in vitroagainst six human tumour cell lines and two nontumourogenic cell lines. Their in vitroactivity against Mycobacterium tuberculosisis also reported. In general, it was found to possess a marginal activity.
URI:	http://hdl.handle.net/10872/8220
ISSN:	1747-5198
Appears in Collections:	Artículos Publicados

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SYNTHESIS AND CRYSTAL STRUCTURE OF (4b,9b)-5-(2,4-DIMETHOXYPHENYL)-4b,9b-7,7-DIMETHYLDIHYDRO-4B,5,6,7,8,9B-HEXAHYDROINDENOL[1,2-B]INDOLE-9,10-DIONE.PDF		132.92 kB	Adobe PDF	View/Open

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