Endemic infection with HTLV-IIB in Venezuelan Indians: molecular characterization.

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Título :	Endemic infection with HTLV-IIB in Venezuelan Indians: molecular characterization.
Autor :	Leon-Ponte, Matilde Echeverria de Perez, Gloria Bianco Colmenares, Nicolás E. Hengst, James Dube, Syamalima Lave, Jayne
Palabras clave :	HTLV-IIB Endemic infection Venezuelan Indians peripheral blood Molecular Characterization HTLV-II NRA
Fecha de publicación :	1998
Editorial :	Journal of acquired immune deficiency syndromes and human retrovirology
Citación :	Vol. 17;No. 5 pp 458-464
Resumen :	The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA.
URI :	http://hdl.handle.net/10872/14843
ISSN :	1077-9450
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