Saber UCV
Repositorio Institucional
Repositorio Institucional
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https://saber.ucv.ve/handle/10872/14843
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| Title: | Endemic infection with HTLV-IIB in Venezuelan Indians: molecular characterization. |
| Authors: | Leon-Ponte, Matilde Echeverria de Perez, Gloria Bianco Colmenares, Nicolás E. Hengst, James Dube, Syamalima Lave, Jayne |
| Keywords: | HTLV-IIB Endemic infection Venezuelan Indians peripheral blood Molecular Characterization HTLV-II NRA |
| Issue Date: | 1998 |
| Publisher: | Journal of acquired immune deficiency syndromes and human retrovirology |
| Series/Report no.: | Vol. 17;No. 5 pp 458-464 |
| Abstract: | The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA. |
| URI: | http://hdl.handle.net/10872/14843 |
| ISSN: | 1077-9450 |
| Appears in Collections: | Artículos Publicados |
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