Saber UCV
Repositorio Institucional
Repositorio Institucional
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https://saber.ucv.ve/handle/10872/14052
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| Title: | Aporphine Alkaloids from Guatteria stenopelata (Annonaceae) |
| Authors: | Rodríguez, María del C. Bastidas, Elsy Rodríguez, Mildred Lucena, Edgard Castillo, Anibal Hasegawa, Masahisa |
| Keywords: | Guatteria stenopelata dicentrinone N-methyldicentrinone 4,5-dioxodehydrodixentrine MAO-B Annonaceae porphine alkaloids |
| Issue Date: | 2008 |
| Publisher: | Natural Products Communications |
| Citation: | Volumen 3, Number 4, Pages 515-518 (2008) |
| Abstract: | Guatteria species (Annonaceae) are rich in isoquinoline alkaloids that contain a restricted beta phenethylamine moiety and thus have potential monoamine oxidase (MAO) inhibitor for treatment of Alzheimer´s and Parkinson´s diseases. Three aporphine alkaloids have bee isolate from G. stenopelata, the know oxoaporphine dicentrinone (1), and two novel compounds, N-methyldicentrinone (2) and 4,5-dioxodehydrodixentrine (3). Their inhibitory effects on MAO-B were evaluated, but none of them was significantly active. |
| URI: | http://hdl.handle.net/10872/14052 |
| ISSN: | 1555-9475 |
| Appears in Collections: | Artículos Publicados |
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