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dc.contributor.authorRodríguez, María del C.-
dc.contributor.authorBastidas, Elsy-
dc.contributor.authorRodríguez, Mildred-
dc.contributor.authorLucena, Edgard-
dc.contributor.authorCastillo, Anibal-
dc.contributor.authorHasegawa, Masahisa-
dc.date.accessioned2017-01-19T15:45:05Z-
dc.date.available2017-01-19T15:45:05Z-
dc.date.issued2008-
dc.identifier.citationVolumen 3, Number 4, Pages 515-518 (2008)en_US
dc.identifier.issn1555-9475-
dc.identifier.urihttp://hdl.handle.net/10872/14052-
dc.description.abstractGuatteria species (Annonaceae) are rich in isoquinoline alkaloids that contain a restricted beta phenethylamine moiety and thus have potential monoamine oxidase (MAO) inhibitor for treatment of Alzheimer´s and Parkinson´s diseases. Three aporphine alkaloids have bee isolate from G. stenopelata, the know oxoaporphine dicentrinone (1), and two novel compounds, N-methyldicentrinone (2) and 4,5-dioxodehydrodixentrine (3). Their inhibitory effects on MAO-B were evaluated, but none of them was significantly active.en_US
dc.language.isoenen_US
dc.publisherNatural Products Communicationsen_US
dc.subjectGuatteria stenopelataen_US
dc.subjectdicentrinoneen_US
dc.subjectN-methyldicentrinoneen_US
dc.subject4,5-dioxodehydrodixentrineen_US
dc.subjectMAO-Ben_US
dc.subjectAnnonaceaeen_US
dc.subjectporphine alkaloidsen_US
dc.titleAporphine Alkaloids from Guatteria stenopelata (Annonaceae)en_US
dc.typeArticleen_US
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