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Título : The Complete Genomic Sequence of an HTLV-II Isolate from a Guahibo Indian from Venezuela
Autor : Dube, Syamalima
Love, Jayne L.
Dube, Dipak K.
Leon-Ponte, Matilde
ECHEVERRÍA DE PÉREZ, GLORIA
Baroja, Miren Lorea
Bianco Colmenares, Nicolás E.
Poiesz, Bernard J.
Palabras clave : Genomic Sequence
Guahibo Indian
HTLV-II
CD3
CD8
T-cell
Fecha de publicación : 1999
Editorial : Virology
Citación : Vol. 253; Nº 2 pp. 181-192
Resumen : A polyclonal CD31, CD81 T-cell line, G2, was derived from the peripheral blood of a seropositive, PCR-positive, HTLV-IIB infected Guahibo Indian from Venezuela. The cell line is productively infected with HTLV-IIB. The entire HTLV-II G2 proviral DNA was sequenced via PCR using overlapping HTLV-II primer pairs. Phylogenetic analyses indicate that HTLV-II G2 is the most divergent HTLV-IIB strain identified to date. Characterization of its deduced proteins and its relationship to other members of the PTLV/BLV genus of retroviruses are discussed.
URI : http://hdl.handle.net/10872/12126
ISSN : 0042-6822
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