Epigenetic Approach on Colorectal Cancer Systemic Therapy: Promising yet a Long Way to Go
Contenido principal del artículo
Resumen
Colorectal cancer (CRC) is the fourth leading cause of cancer-related deaths worldwide. Various genetic and epigenetic changes in colonic epithelial cells, including DNA methylation, histone modifications, and noncoding RNAs, were involved in the initiation and progression of CRC. Moreover, epigenetic changes played an important role in CRC drug resistance. The dynamic and reversibility of epigenetic changes provide new possible therapeutic targets for colorectal cancer.
Descargas
Los datos de descargas todavía no están disponibles.
Detalles del artículo
Cómo citar
Ayu Rezkitha, Y. A. ., Aji Savitri, C. M. ., Lusida, M. I. ., Yudho Bintoro, S. . U. ., Rahmawati, L. D. ., I’tishom, R. ., & Miftahussurur, M. . (2022). Epigenetic Approach on Colorectal Cancer Systemic Therapy: Promising yet a Long Way to Go. Gaceta Médica De Caracas, 130(2). Recuperado a partir de http://saber.ucv.ve/ojs/index.php/rev_gmc/article/view/24057
Número
Sección
ARTÍCULOS DE REVISIÓN
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.