Efectos de un protocolo de ayuno intermitente sobre la composición corporal y perfil lipídico en estudiantes universitarios

Autores

  • Víctor Toro Román Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura
  • Diego Muñoz Marín Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura
  • Jesús Siquier Coll Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura
  • Ignacio Bartolomé Sánchez Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura
  • Julio Montero Arroyo Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura
  • Mario Pérez Quintero Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura
  • Marcos Maynar Mariño Facultad de Ciencias del Deporte. Laboratorio de Fisiología del Ejercicio. Universidad de Extremadura

Palavras-chave:

Salud, Dieta, Composición Corporal, Colesterol, Ayuno Intermitente, Health, Diet, Body Composition, Cholesterol, Intermittent Fasting

Resumo

El ayuno intermitente es una estrategia nutricional de creciente interés para el control del peso y mejora de la salud metabólica. El objetivo del presente estudio fue evaluar el efecto de un protocolo de ayuno intermitente sobre la composición corporal, perfil lipídico y los biomarcadores de riesgo cardiovascular en estudiantes universitarios. En este estudio experimental participaron 30 sujetos varones y fueron divididos aleatoriamente en dos grupos, 15 sujetos constituían el grupo experimental (GE) (edad: 20,83±0,98 años) y 15 el grupo control (GC) (edad: 23,71±5,55 años). El GE realizó un protocolo de ayuno 16/8, dieciséis horas de ayuno y ocho horas de ingesta calórica sin limitaciones, dos días consecutivos a la semana durante cinco semanas. Se evaluó la composición corporal, la ingesta calórica, el perfil lipídico y los biomarcadores del riesgo cardiovascular al inicio, mitad y final del protocolo. Se observaron descensos significativos en el GE en pliegues cutáneos, perímetro cintura, porcentaje de grasa, perfil lipídico y biomarcadores del riesgo cardiovascular en comparación con GC (p<0,05). Se encontraron incrementos significativos en la ingesta de colesterol y ácidos grasos poliinsaturados en el GE al final del estudio (p<0,05). Se observaron descensos en el colesterol total, triglicéridos, lipoproteínas de baja densidad y biomarcadores del riesgo cardiovascular a lo largo del protocolo en el GE (p<0,05). Un protocolo de ayuno intermitente 16/8, dos días consecutivos por semana, durante cinco semanas, parece efectivo para mejorar parámetros de composición corporal y perfil lipídico, así como para mejorar los biomarcadores relacionados con el riesgo cardiovascular.

Intermittent fasting is a nutritional strategy of high interest in weight control and improvement of metabolic health. The objective of this study was to evaluate the effect of an intermittent fasting protocol on body composition, lipid profile and biomarkers of cardiovascular risk in university students. In this experimental study thirty male subjects participated and were randomly divided into two groups; fifteen subjects constituted the experimental group (GE) (age: 20.83 ± 0.98 years) and fifteen the control group (GC) (age: 23.71 ± 5.55 years). The GE performed a fasting protocol 16/8, sixteen hours of fasting and eight hours of caloric intake without limitations, two consecutive days per week for five weeks. Body composition, calorie intake, lipid profile and biomarkers of cardiovascular risk were evaluated at the beginning, middle and at the end of the protocol. Significant decreases were found in GE in skinfolds, waist perimeter, % fat, lipid profile and biomarkers of cardiovascular risk as compared to GC (p <0.05). There were significant increases in the intake of cholesterol and polyunsaturated fatty acids in the GE at the end of the study (p <0.05). There were decreases in total cholesterol, triglycerides, low-density lipoproteins, and biomarkers of cardiovascular risk throughout the study in GE (p<0.05). An intermittent fasting protocol 16/8, two consecutive days per week, for five weeks, seems effective to improve parameters of body composition and lipid profile, as well as to improving biomarkers related to cardiovascular risk

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Referências

REFERENCIAS

Wilson RA, Deasy W, Stathis CG, Hayes A, Cooke MB. Intermittent Fasting with or without Exercise Prevents Weight Gain and Improves Lipids in Diet-Induced Obese Mice. Nutrients. 2018;10(3):346.

Crittenden AN, Schnorr SL. Current views on hunter-gatherer nutrition and the evolution of the human diet. Am J Phys Anthropol. 2017;162:84–109.

Albero R, Sanz A, Playán J. Metabolismo en el ayuno. Endocrinol y Nutr. 2004;51(4):139–48.

Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res Rev. 2016;39:46–58.

Anton S, Moehl K, Donahoo WT, Marosi K, Lee SA, Mainous AG, et al. Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting. Obesity. 2018;26(2):254–68.

Porta J, Galiano D, Tejedo A, González JM. Valoración de la composición corporal. Utopías y realidades. In: Esparza F, editor. Manual de Cineantropometría Monografías. Madrid; 1993. p. 113–70.

Moreiras O, Carbajal A, Cabrera L, Cuadrado C. Tabla de composición de alimentos. 16a. Madrid: Editorial Pirámide; 2013.

Hagströmer M, Oja P, Sjöström M. The International Physical Activity Questionnaire (IPAQ): a study of concurrent and construct validity. Public Health Nutr. 2006;9(6):755–62.

Kuksis A, Myher JJ, Marai L, Geher K. Determination of plasma lipid profiles by automated gas chromatography and computerized data analysis. J Chromatogr Sci. 1975;13(9):423–30.

Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18(6):499–502.

Lemieux I, Lamarche B, Couillard C, Pascot A, Cantin B, Bergeron J, et al. Total cholesterol/HDL cholesterol ratio vs LDL cholesterol/HDL cholesterol ratio as indices of ischemic heart disease risk in men: the Quebec Cardiovascular Study. Arch Intern Med. 2001;161(22):2685–92.

Varady K, Bhutani S, Klempel M, Kroeger C, Trepanowski J, Haus J, et al. Alternate day fasting for weight loss in normal weight and overweight subjects: A randomized controlled trial. Nutr J. 2013;12(1):146.

Syam AF, Sobur CS, Abdullah M, Makmun D. Ramadan fasting decreases body fat but not protein mass. Int J Endocrinol Metab [Internet]. 2016 Jan 2;14(1):e29687. Available from: http://endometabol.neoscriber.org/en/articles/17718.html

Mirzaei B, Rahmani-Nia F, Moghadam M, Ziyaolhagh S, Rezaei A. The effect of Ramadan fasting on biochemical and performance parameters in collegiate wrestlers. Iran J Basic Med Sci. 2012;15(6):1215–20.

Clayton DJ, Creese M, Skidmore N, Stensel DJ, James LJ. No effect of 24 h severe energy restriction on appetite regulation and ad libitum energy intake in overweight and obese males. Int J Obes. 2016;40(11):1662–70.

Chowdhury E, Richardson J, Tsintzas K, Thompson D, Betts J. Effect of extended morning fasting upon ad libitum lunch intake and associated metabolic and hormonal responses in obese adults. Int J Obes. 2016;40(2):305–11.

Santos HO, Macedo RCO. Impact of intermittent fasting on the lipid profile: Assessment associated with diet and weight loss. Clin Nutr ESPEN. 2018;24:14–21.

Klempel M, Kroeger C, Varady K. Alternate day fasting increases LDL particle size independently of dietary fat content in obese humans. Eur J Clin Nutr. 2013;67(7):783–5.

Tao R, Xiong X, DePinho RA, Deng C-X, Dong XC. Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6. J Lipid Res. 2013;54(10):2745–53.

Klop B, Elte JWF, Cabezas MC. Dyslipidemia in Obesity: Mechanisms and Potential Targets. Nutrients. 2013;5(4):1218–40.

Gur E, Turan G, Ince O, Karadeniz M, Tatar S, Kasap E, et al. Effect of Ramadan fasting on metabolic markers, dietary intake and abdominal fat distribution in pregnancy. Hippokratia. 2015;19(4):298–303.

Hammouda O, Chtourou H, Aloui A, Chahed H, Kallel C, Miled A, et al. Concomitant effects of Ramadan fasting and time-of-day on apolipoprotein AI, B, Lp-a and homocysteine responses during aerobic exercise in Tunisian soccer players. PLoS One. 2013;8(11):1–9.

Haas JT, Staels B. Cholesteryl-ester transfer protein (CETP): A Kupffer cell marker linking hepatic inflammation with atherogenic dyslipidemia? Hepatology. 2015;62(6):1659–61.

Shinkai H. Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases. Vasc Health Risk Manag. 2012;8:323–31.

Orozco-Beltran D, Gil-Guillen VF, Redon J, Martin-Moreno JM, Pallares-Carratala V, Navarro-Perez J, et al. Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study. PLoS One. 2017

Como Citar

Toro Román, V., Muñoz Marín, D., Siquier Coll, J., Bartolomé Sánchez, I., Montero Arroyo, J., Pérez Quintero, M., & Maynar Mariño, M. (2020). Efectos de un protocolo de ayuno intermitente sobre la composición corporal y perfil lipídico en estudiantes universitarios. Archivos Latinoamericanos De Nutrición (ALAN), 69(3), 157–164. Obtido de http://saber.ucv.ve/ojs/index.php/rev_alan/article/view/19267

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