Estimación de algunos parámetros de la función renal en pacientes con COVID-19 en la provincia de Karbala
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parámetros sanguíneos, SOP2, COVID19, géneroResumen
En casos con trastornos del sistema respiratorio de moderados a extremos, también se han involucrado la Enfermedad por Virus Corona 2019 (COVID-19) o SRAS-CoV-2 (Síndromes respiratorios agudos graves por coronavirus 2). El objetivo de esta investigación es la asociación entre diferentes parámetros hematológicos y la gravedad de COVID19. 184 pacientes con COVID-9 ingresados en octubre de 2020 hasta febrero de 2021 en el Hospital de Especialidades de Karbala en la provincia de Karbala Los registros de salud recopilaron informes clínicos y de laboratorio de los pacientes. Entre ellos, el grupo demográfico moderado estaba compuesto por 42 (22,8%) 88 (47,8%) y el grupo de grave / amenaza para la vida estaba compuesto por 54 (29,3%) pacientes. Hubo diferencias significativas en los parámetros sanguíneos en el resultado del presente análisis (urea, creatinina, ferritina y spo2). Infección por COVID 19 en varias etapas (leve, moderada y grave)
CONCLUSIÓN: En nuestra investigación se observó la alta incidencia de insuficiencia renal en pacientes con COVID-19. Los hallazgos mostraron una asociación importante entre los índices de función renal y las distorsiones en varios marcadores de laboratorio.
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- Zhu H, Wei L, Niu P. The novel coronavirus outbreak in Wuhan, China. Glob Health Res Policy 2020; 5: 6.
- World Health Organization. WHO Director-General's opening remarks at the media briefing on COVID-19 - 30 October 2020. WHO. 2020: https://www.who.int/publications/m/item/weekly-operational-update---30-october-2020
- Hoehl S, Rabenau H, Berger A, Kortenbusch M, Cinatl J, Bojkova D, et al. Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China. N Engl J Med. 2020; 382: 1278-1280
- Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020; 8: 420-422.
- Haick A.K., Rzepka J.P., Brandon E., Balemba O.B., Miura T.A. Neutrophils are needed for an effective immune response against pulmonary rat coronavirus infection, but also contribute to pathology. J Gen Virol. 2014;95:578–590. doi: 10.1099/vir.0.0619860. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
- Didangelos A. COVID19 hyperinflammation: what about neutrophils? mSphere. 2020;5(3) doi: 10.1128/mSphere.0036720. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
- Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention. JAMA 2020 Apr;323(13):1239-1242
- Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM, et al. China medical treatment expert group for COVID-19. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J 2020 May;55(5):2000547
- Lindner D, Fitzek A, Bräuninger H, Aleshcheva G, Edler C, Meissner K, et al. Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiology. 2020
- Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020 Feb;395(10223):507-513
- Shi Y, Wang Y, Shao C, Huang J, Gan J, Huang X, et al. COVID-19 infection: the perspectives on immune responses. Cell Death & Differentiation. 2020 2020/03/23
- Yang L, Liu S, Liu J, Zhang Z, Wan X, Huang B, et al. COVID-19: immunopathogenesis and Immunotherapeutics. Signal Transduction and Targeted Therapy. 2020 2020/07/25;5(1):128.
- Lindner D, Fitzek A, Bräuninger H, Aleshcheva G, Edler C, Meissner K, et al. Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiology. 2020.
- Connors JM, Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood. 2020;135(23):2033-40
- Hachim IY, Hachim MY, Naeem KB, Hannawi H, Salmi IA, Hannawi S. Male Gender is a risk factor for sever form of COVID-19 illness and worse outcome in the Middle East. Research Square. 2020.
- Naicker S, Yang CW, Hwang SJ, Liu BC, Chen JH, Jha V. The novel coronavirus 2019 epidemic and kidneys. Kidney Int 2020 May;97(5):824-828
- Li Z, Wu M, Yao J, Guo J, Liao X, Song S, et al. Caution on kidney dysfunctions of 2019-nCoV patients. medRxiv 2020020820021212. 2020
- Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L. Acute kidney injury in critically ill patients with COVID-19. Intensive Care Med 2020 Jul;46(7):1339- 1348
- Cheng Y, Luo R, Wang K, et al. Kidney disease is associated with in-hospital death of patients with COVID19. Kidney Int. 2020;97(5):829–838.
- Boroujeni EK, Kellner SJ, Pezeshgi A. Covid-19 and kidney; a mini-review on current concepts and new data. Journal of Nephropharmacology.;10(1):2021
- Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395:497- 506. doi: 10.1016/ S0140-6736(20)30183-5
- Betjes MG. Immune cell dysfunction and inflammation in end-stage renal disease. Nat Rev Nephrol. 2013; 9:255-65. doi: 10.1038/nrneph.2013.44.
- Eskandari Naji H, Ghorbanihaghjo A, Argani H, Raeisi S. Serum sTWEAK and FGF-23 Levels in Hemodialysis and Renal Transplant Patients. Int J Organ Transplant Med. 2017; 8:110-116.
- Fei Zhou, Ting Yu, Ronghui Du, Guohui Fan, Ying Liu, Zhibo Liu, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–62
- Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020; 395(10223):507–13
- Tao Liu, Jieying Zhang, Yuhui Yang, Hong Ma, Zhengyu Li, Jiaoyu Zhang, et al. The potential role of IL-6 in monitoring severe case of coronavirus disease 2019. medRxiv 2020.03.01.20029769; doi: https://doi.org/10.1101/2020.03.01.20029769
- Isam, J.Z., Kamil, K.Z. and Banoon Shaima, R., Review about COVID-19. Research Journal of Biotechnology (2021)Vol, 16(4).
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