The relationship between fetuin-A levels and ovarian cyst in Kirkuk women
Keywords:
ovarian cyst; Fetuin-A; MalondialdehydeAbstract
The current study mainly aims to reveal the relationship between fetuin-A levels and ovarian cysts. A purposive sample of women with ovarian cysts visiting Azadi and Al-Jumhuri Hospitals in Kirkuk City is selected according to the study criteria. The study samples include 50 women with ovarian cysts and 20 as controls. The current study's findings exhibited that the highest duration of marriage was one year in patients and control groups (56%, and 60%, respectively). Menstruation in the patients' group was irregular (100%). Abortion in the patients' group reached 86%. The percentage of hereditary disease in patients and control groups were 82% and 90%, respectively. Otherwise, Fetuin-A and Malondialdehyde (MDA) levels in women with ovarian cysts demonstrate significant (P < 0.05) elevated compared with the control women.
Downloads
References
Grimes DA, Jones LB, Lopez LM, Schulz KF. (2014). Oral contraceptives for functional ovarian cysts. Cochrane Database Syst Rev. 4: CD006134.
Abduljabbar H. S.; Yasir A.; Estabrq G.; Ghazal S. and Afnan A. (2015). Review of 244 cases of ovarian cysts. Saudi Med J. 36 (7): 834-838.
Karina C. Nivel de conocimiento sobre Diabetes Mellitus que tienen los pacientes diagnosticados del servicio médico Sanitas de Venezuela entre diciembre 2015 a julio 2016. Diabetes Internacional. 2017;9(1):1.
Grimes DA. and Hughes JM. (1989). Use of multiphasic contraceptives and hospitalizations of women with functional ovarian cyst in the United States. Obstet Gynecol. 73: 1037–9
Hongqian L.; Xiangao W, Donghao L, Zhihong L. and Gang S. (2013). Ovarian masses in children and adolescents in China: analysis of 203 cases. J Ovarian Res. 6: 47.
Maliheh A, Tahereh A, Soghra Y, Giti N, Kourosh S. (2012). Functional ovarian cysts: a Multicenter study of the current management among Iranian patients. Shiraz E-Medical Journal vol. 13, No.3.
Israa H. A.; Ruqiya S. T. and Zuhud M. (2017). Ovarian Cysts in Unmarried Women in Tikrit City. Med. J. Tikrit Uni. 23(1): 105-112.
Crofton M. Gynecological Imaging. In: Sutton D, editor. Textbook of radiology and imaging.7th edition. Philadelphia: Churchill Livingstone; 2002. p.1069-1104.
Jaffar, T. O. and Saeed N. Y. (2013). Validity of ultrasound in detecting benign and malignant ovarian cysts. Ann. Coll. Med. Mosul. 39(1): 53-58.
Wojtysiak-Duma B.; Malecha Jędraszek A, Burska A, Duma D. and Donica H. (2010). Serum fetuin-A levels in patients with type 2 diabetes mellitus. Ann UMCS Sect DDD. 2(14):93-9.
Kettler M, Bongartz P, Westenfeld R, Wildberger JE, Mahnken AH, Böhm R, Metzger T, Wanner C, Jahnen-Dechent W. and Floege J. (2003). Association of low fetuin-A (AHSG) concentration in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. The Lancet. 361(9360):827-33.
Dabrowskaa, A. M.; Jerzy S. T.; Beata W. and Dariusz D. (2015). Fetuin-A (AHSG) and its usefulness in clinical practice. Review of the literature. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 159(3):352-359.
Trepanowski, J.F.; Mey, J.; Varady, K.A. Fetuin-A: A novel link between obesity and related complications. Int. J. Obes. 2015, 39, 734–741.
Mathews ST, Chellam N, Srinivas PR, Cintron VJ, Leon MA, Goustin AS. (2000). Alpha2-HSG, a speci¿ c inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor. Mol Cell Endocrinol. 164(1-2):87-98.
Brown WM.; Dziegielewska KM, Saunders’ NR, Christie DL, Nawratil P. and Muller-Esterl W. (1992). The nucleotide and deduced amino acid structures of sheep and pig fetuin. Common structural features of the mammalian fetuin family. Eur J Biochem. 205(1):321-31.
Rehncrona, S.; Smith, D.S.; Akesson, B.; Westerberg, E. and Siesjo, B.K.(1980). Peroxidative changes in brain cortical fatty acids and phospholipids as characterized during Fe +2 and ascorbic acid-stimulated lipid peroxidation in vitro. J. neurochemistry. 34: 1630-38.
Enli Y.; Fenkci SM, Fenkci V. and Oztekin O. (2013).SerumFetuin-Alevels, insulin resistance and oxidative stress inwomen with polycystic ovary syndrome. J Gynecol Endocrinol. 29:1036-9.
Kozakowski J.; Jeske W. and Zgliczyński W. (2014). Fetuin-Alevelsin lean and obese women with polycystic ovary syndrome. J Endokrynol Pol. 65:371-6.
Sak S.; Uyanikoglu H.; Incebiyik A, Incebiyik H, Hilali NG, Sabuncu T. and Sak E. (2018). Associations of serum fetuin-A and oxidative stress parameters with polycystic ovary syndrome. J Clin Exp Reprod Med.45:116-21.
Abali R.; Celik C, Tasdemir N, Guzel S, Alpsoy S, Yuksel A. and Celik E. (2013). The serum protein α2-Heremans-Schmid glycoprotein/fetuin-aconcentration and carotid intimamedia thickness in women with polycystic ovary syndrome. J Eur J Obstet Gynecol Reprod Biol. 169:45-49.
Díaz M.; Gallego-Escuredo J. M. and López-Bermejo A. (2018). Low-Dose Spironolactone-Pioglitazone-Metformin Normalizes Circulating Fetuin-A Concentrations in Adolescent Girls with Polycystic Ovary Syndrome. J Int J Endocrinol. 4192940.
Remzi A.; Cem C.; Nicel T.; Savas G.; Seref A. and Aytac Y. (2013). The serum protein α2-Heremans-Schmid glycoprotein/fetuin-a concentration and carotid intima-media thickness in women with polycystic ovary syndrome. European Journal of Obstetrics & Gynecology and Reproductive Biology 169: 45-49.
Gulhan I.; Bozkaya G, Oztekin D, Uyar I, Kebapcilar A. and Pamuk B. (2012). Serum Fetuin-A levels in women with polycystic ovary syndrome. Arch Gynecol Obstet. 286: 1473-1476.
Pasquali R.; Gambineri A. and Pagotto U. (2006). The impact of obesity on reproduction in women with polycystic ovary syndrome. BJOG. 113:1148‐1159.
Erdogan M.; Karadeniz M.; Berdeli A, Alper G, Caglayan O. and Yilmaz C. (2008). The relationship of the interleukin-6 -174 G>C gene polymorphism with oxidative stress markers in Turkish polycystic ovary syndrome patients. J Endocrinol Invest. 31(7):624-9.
Gonzalez F.; Rote NS.; Minium J. and Kirwan JP. (2006). Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome. J Clin Endocrinol Metab. 91:336-40.
Turan V, Sezer ED, Zeybek B and Sendag F. (2015). Infertility and the presence of insulin resistance are associated with increased oxidative stress in young, non-obese Turkish women with polycystic ovary syndrome. J. Pediatric and Adolescent Gynecology. 28 119–123.
Orellana IS, Villota BV, Palacios CJ, Altamirano IZ, Paredes MG, Crespo DO, Yaucan GQ, Altamirano JA, Carrasco AM, Vela VR, Villacreses GO. Infección por bacterias multirresistentes en pacientes con trauma cráneo encefálico del servicio de terapia intensiva del hospital Luis Vernaza, Ecuador. Archivos Venezolanos de Farmacología y Terapéutica. 2020;39(6):721-7.
Tibanta DL, Ortiz AG, Yumiseba MA, Caisaguano AT, González RG, Haro TB, Granja AP, Bohórquez GB, Jiménez EB, Morales DC, Buenaño FM. Incidencia y características clínicas de lactantes menores con neumonía adquirida en la comunidad ingresados en el Hospital Pediátrico “Baca Ortiz”, Ecuador. Archivos Venezolanos de Farmacología y Terapéutica. 2020;39(4):410-3.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 AVFT – Archivos Venezolanos de Farmacología y Terapéutica
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
