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> Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione
Please use this identifier to cite or link to this item: https://saber.ucv.ve/handle/10872/4815

Title: Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione
Authors: Lobo, Gricela
Zuleta, Elimar
Charris, Katiuska
Cappareli, Mario
Briceño, Alexander
Ángel, Jorge
Charris, Jaime
Keywords: indeno[1,2-b]indole, ninhydrin, regiospecific,
crystal structure
Issue Date: 15-Apr-2011
Abstract: A highly regiospecific synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-7,7-dimethyl-4b,9bdihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b]indole-9,10-dione is reported. It was tested in vitroagainst six human tumour cell lines and two nontumourogenic cell lines. Their in vitroactivity against Mycobacterium tuberculosisis also reported. In general, it was found to possess a marginal activity.
URI: http://hdl.handle.net/10872/4815
ISSN: 1747-5198
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