Repositorio Institucional
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https://saber.ucv.ve/handle/10872/4815
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| Title: | Synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-4b,9b-7,7-dimethyldihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b] indole-9,10-dione |
| Authors: | Lobo, Gricela Zuleta, Elimar Charris, Katiuska Cappareli, Mario Briceño, Alexander Ángel, Jorge Charris, Jaime |
| Keywords: | indeno[1,2-b]indole, ninhydrin, regiospecific, crystal structure |
| Issue Date: | 15-Apr-2011 |
| Abstract: | A highly regiospecific synthesis and crystal structure of (4bRS,9bRS)-5-(2,4-dimethoxyphenyl)-7,7-dimethyl-4b,9bdihydroxy-4b,5,6,7,8,9b-hexahydroindeno[1,2-b]indole-9,10-dione is reported. It was tested in vitroagainst six human tumour cell lines and two nontumourogenic cell lines. Their in vitroactivity against Mycobacterium tuberculosisis also reported. In general, it was found to possess a marginal activity. |
| URI: | http://hdl.handle.net/10872/4815 |
| ISSN: | 1747-5198 |
| Appears in Collections: | Artículos Publicados |
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