Presence Of Autoantibodies Following Sars-Cov-2 Infection And Prolonged Symptoms.

Abstract

Since the emergence of COVID-19, there have been case reports with development of autoimmune or autoinflammatory conditions following acute infection. SARS-CoV-2 has the ability to induce a state of hyperstimulation with increased synthesis of multiple autoantibodies, demonstrated in different studies evaluating the presence of autoantibodies. This systemic autoreactivity suggests autoimmune activation during and/or following SARSCoV-2 infection. The persistent positivity of autoantibodies has led to the conclusion that, in a group of people, production is maintained and may lead to the symptoms of long COVID. Our study evaluated the presence of post-COVID-19 symptoms and autoantibody positivity in convalescents.