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> Oral manifestations associated to Paracoccidioidomicosis and Histoplasmosis
Please use this identifier to cite or link to this item: https://saber.ucv.ve/handle/10872/18551

Title: Oral manifestations associated to Paracoccidioidomicosis and Histoplasmosis
Authors: Merino-Alado, Rommie
Mata-Essayag, Sofia
Pineda, Jacinto
Moronta, Gustavo
Briceño, Elsi
Mujica, Valentina
Landaeta, María Eugenia
Garrido, Liseloth
Keywords: Paracoccidioidomicosis
Histoplasmosis
oral manifestations
Issue Date: 26-May-2018
Abstract: Objective: To determine the frequency and clinical forms of oral manifestations associated to Paracoccidioidomycosis (PCM) and Histoplasmosis. Material and Methods: 481 medical records of outpatients referred to the Medical Mycology Department were reviewed since 2009 to 2016. Data were analyzed using descriptive statistical methods. Results: 47 (9.77%) cases had oral manifestations, 29 (61.70%) were associated to PCM and 18 (38.29%) to histoplasmosis. For PCM, male-female ratio was 8:1 and 1:1 for histoplasmosis. The average age for PCM was 48 years old and 53 for histoplasmosis. All the PCM patients had more than 1 oral structure affected: 44.82% were gingival lesions and 27.58% palate. In patients with histoplasmosis, 6 (33.33%) were lesions affecting palate and 6 (33.33%) involving tongue. For both entities, painful ulcers and granulomatous-like lesions were the most prevalent clinical forms; however, we observed a wide range of other oral manifestations. Regarding PCM patient’s comorbidities, 3 (10.34%) cases had HIV/AIDS, 8 (27.58%) histoplasmosis and 2 (6.89%) carcinomas. Whereas the comorbidities of patients with histoplasmosis, 2 (11.11%) had HIV/AIDS and 1 (5.55%) had carcinoma. Conclusion: In endemic countries for both mycoses, dentists must be aware of patients with mouth lesions, take advantage of epidemiologic clues that suggest risk factors and be acquainted with all the current diagnostic tests in order to make a quick diagnosis and treatment in highly suspicious cases.
URI: http://hdl.handle.net/10872/18551
ISSN: 1519-0501
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