Saber UCV
Repositorio Institucional
Repositorio Institucional
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https://saber.ucv.ve/handle/10872/177
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| Title: | Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats |
| Authors: | Israel, Anita Barbella, Yarisma |
| Keywords: | Arterial natriuretic peptide Natriuresis Diuresis lntracerebroventricular adminislrati Fluid homeostasis |
| Issue Date: | 31-Mar-1986 |
| Publisher: | Bnin Research Bulletin |
| Series/Report no.: | Vol. 17;l4l-144. I986 |
| Abstract: | BRAIN RES BULL l7(2) l4l-144, 1986.-lntracerebroventricular (lVT) administration of rat atrial peptide (6-33) (rANP) to conscious male hydrated or salt-loaded rats, resulted in significant increase in urinary volume. The diuretic effects of rANP occurred during the 3 hr period of urine collection and were most effective during the first hour. Most remarkably. rANP given IVT produced a dose-related increase in urinary sodium excretion at 3 hr. With a high dose of rANP. kaliuresis was significant only at 3 hr. Our results strongly suggest that ANF may play a significant role in central regulalion of fluid homeostasis. and that its natriuretic and diuretic effects may be. at least in paft, centrally mediated |
| URI: | http://hdl.handle.net/10872/177 |
| Appears in Collections: | Artículos Publicados |
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