Saber UCV
Repositorio Institucional
Repositorio Institucional
Please use this identifier to cite or link to this item:
https://saber.ucv.ve/handle/10872/169
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| Title: | High-affinity angiotensin receptors in rat adrenal medulla |
| Authors: | Israel, Anita Niwa, Masami Plunkett, Laura M. Saavedra, Juan M. |
| Keywords: | angiotensin II receptors rat adrenal medulla receptor autoradiography |
| Issue Date: | 29-Apr-1985 |
| Publisher: | Regulatory Peptídes |
| Series/Report no.: | ll (t985);237 243 |
| Abstract: | Angiotensin II receptors have been quantitated in single rat adrenal medullas by incubation oftissue sections with r r sl-[Sarr]-AII, autoradiography with exposure to 3H-sensitive Ultrofllm, computerized densitometry and comparison with r25l-labelled standards. Rat adrenal medulla contains a single class of high affinity AII receptors with a ¡<" of0.84 + 0.02 x lOe M rand a B^.,of3259 + 502 fmol/mg protein, one of the highest densities in AII receptors found in rat tissues. These observations provide evidence for a local site ofaction of AII in the release ofadrenal medullary catecholamines. |
| URI: | http://hdl.handle.net/10872/169 |
| Appears in Collections: | Artículos Publicados |
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