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Please use this identifier to cite or link to this item: https://saber.ucv.ve/jspui/handle/10872/14060
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dc.contributor.authorParedes, A.-
dc.contributor.authorHasegawa, Masahisa-
dc.contributor.authorPrieto, F.-
dc.contributor.authorMéndez, Jeannette-
dc.contributor.authorRodríguez, María del C.-
dc.contributor.authorRodríguez-Ortega, M.-
dc.date.accessioned2017-01-19T20:02:35Z-
dc.date.available2017-01-19T20:02:35Z-
dc.date.issued2001-
dc.identifier.citation78 (2001) 129–132en_US
dc.identifier.issn0022-3573-
dc.identifier.urihttp://hdl.handle.net/10872/14060-
dc.description.abstractMethanolic extract of leaves and twigs of Guatteria cardoniana R.E. Fries (Annonaceae), a plant from the Venezuelan rain forest, was separated in alkaloid rich fractions and their biological effect on baby hamster kidney (BHK) cell line was studied. The initial plant extract (FA) induced cell proliferation, cytotoxicity as well as antiviral activity, depending on the concentration used. Further separation of this methanolic extract allowed us to separate these biological activities. The fraction with the highest antiviral activity (F7) was chromatographed and three of the nine alkaloid-rich fractions obtained, retained this activity. One of them (F711) exhibited the highest inhibitory effect against a neurotropic Sindbis virus (NSV).en_US
dc.language.isoenen_US
dc.publisherJournal of Ethno-Pharmacologyen_US
dc.subjectAnnonaceaeen_US
dc.subjectGuatteria cardonianaen_US
dc.subjectAntiviralen_US
dc.subjectSindbis virusen_US
dc.titleBiological activity of Guatteria cardoniana fractionsen_US
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