Saber UCV
Repositorio Institucional
Repositorio Institucional
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https://saber.ucv.ve/handle/10872/13946
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| Title: | Cell-Mediated Effector Mechanisms in Aging Humans |
| Authors: | Marcano, Norka B. Rivas, Alberto Feo F., Elizabeth Blanca, Isaac Penchaszadeh, Graciela K. Pérez-Rojas, Gloria Bianco Colmenares, Nicolás E. |
| Keywords: | Specific nonspecific alloantigens Tckiller cells cell-mediated Iympholysis RhD+ |
| Issue Date: | 1982 |
| Publisher: | lnternational Archives of Allergy and Applied Immunology |
| Series/Report no.: | Vol.69;Nº 1 pag. 7-11 |
| Abstract: | Specific and nonspecific cell-mediated effector mechanisms have been simultaneously assayed in 15 aged humans. 8 were female and 7 male, including a 114-year-old male in remarkably good health. Proliferative response to alloantigens, the generation of T killer cells and the ability to express cell-mediated Iympholysis as well as the presence of natural cell-mediated cytotoxicity against K562 tumor cell line and the capacity to mount an ADCC response to RhD+ human red blood cell sensitized with anti-D antisera, revealed that in the human aged, while T function significantly declines, nonspecific cell mediated effector mechanisms are operative. |
| URI: | http://hdl.handle.net/10872/13946 |
| ISSN: | 0020-5915 |
| Appears in Collections: | Artículos Publicados |
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