HLA COMPLEX IN WERNER'S DISEASE

Abstract

During the 8th International Workshop, we studied family 01, where five patients with Werner's disease were identified in the first generation. Werner's Syndrome is a rare entity with a recessive pattern of inheritance where consanguinity between parents is expected to be increased . In our family we found that individuals 300 and 301 were first cousins It is relevant at this point to rep ort that this family comes from Quibor, a small town in Venezuela, where a group of German immigrants sett led in the middle of t he 19th century, creating a highly inbred population. Quibor still maintains some German characteristics in architecture, habits, and people with Caucasian features.