Saber UCV
Repositorio Institucional
Repositorio Institucional
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https://saber.ucv.ve/handle/10872/13832
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| Title: | Epidermal Immune Privilege in American Cutaneous Leishmaniasis |
| Authors: | Tapia, Félix J. Cáceres–Dittmar, Gisela Sánchez, Martín A. |
| Keywords: | immune system cells Langerhans cells dermal cells T cells dermal perivascular unit endothelial venules dendritic cell |
| Issue Date: | 1996 |
| Publisher: | Molecular and immune mechanisms in the pathogenesis of cutaneous leishmaniasis. |
| Series/Report no.: | pp. 139-150; |
| Abstract: | The skin is an important component of the immune system conforming a particular microenviroment referred to as the skill immune system (SIS). The SIS includes immunocompetent cells such as Langerhans cells, keratinocytes, dermal cells and cutaneous-specifie T cells, the dermal perivascular unit, and epidermal and dermal humoral constituent that involve interacting; cytokines and chemokines. The perivascular unit embraces the high endothelial venules (HEV), T cells, mast cells and dermal dendrocytes." The Langerhans cells, which are members of the dendritic cell family, are the professional omnipresent antigen-presenting cell (APC) of the epidermis, In contrast, keratinocytes become active immunocompetent cell solely after a cutaneous stimulus. |
| URI: | http://hdl.handle.net/10872/13832 |
| ISBN: | 3-540-61198-3 |
| Appears in Collections: | Artículos Publicados |
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