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> Cojedes: a leprosy hyperendemic state
Please use this identifier to cite or link to this item: https://saber.ucv.ve/handle/10872/13008

Title: Cojedes: a leprosy hyperendemic state
Authors: Aranzazu, Nacarid
Parra, Juan J
Cardenas, Maritza
Rada, Elsa
Zerpa, Olga
Rivera, Teresa
Borges, Rafael
Gonzalez, Pablo
Morales, Jose
Sosa, Ramon
Sanchez, Forquis
Convit, Jacinto
Keywords: leprosy
hyper-endemic state
prevalence
Issue Date: 1-May-2012
Publisher: International Journal of Dermatology
Abstract: Leprosy is a chronic infectious disease produced by Mycobacterium leprae. In 1997 Venezuela reached the goal of elimination of leprosy as a public health problem (according to the World Health Organization a prevalence rate of £1/10,000 inhabitants), but five states still had prevalence rates over that goal. For this study we selected Cojedes State, where prevalence rates remain over the elimination goal. Objective Evaluate the real leprosy situation in high-prevalence areas of Cojedes State. Materials and methods Seven communities of Cojedes State were selected because they had the highest historic prevalence, as well as the highest prevalence in the year to be studied (1997). Results A rank correlation using Spearman’s test comparing historical prevalence rates (1946–1996) and detection rates (1998–2004) gave a statistically significant P < 0.05 value. Diagnosed leprosy cases were as follows: age: 3.2% under 15 years old; sex: male/female rates between 60% and 91.66% males. The highest number of cases were paucibacillary forms: indeterminate leprosy (33.07%) and borderline tuberculoid leprosy (32.28%);tuberculoid leprosy (7.00%); and multibacillary cases (lepromatous leprosy, LL) were only 2.36%. Bacteriologically, 18.52 patients were M. leprae positive. At the moment of diagnosis, 96.6% showed no disabilities, 3.4% showed grade I disabilities, and there were no grade II or III disabilities. Conclusion This study confirms that several communities in Cojedes State have extremely high leprosy rates.
URI: http://hdl.handle.net/10872/13008
ISSN: 0011-9059
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