Comparison of the effect of compression stockings with heparin and enoxaparin in the prevention of deep vein thrombosis in lower limbs of hysterectomy patients

Resumen

Introduction: Deep vein thrombosis is a common complaintin patients which can be caused by factors such assurgery. Medical and mechanical methods such as stockingsare used to prevent this complication. Although severalstudies have examined and compared the effects ofthese methods, is no study has compared these methodsin hysterectomy. The purpose of the current research wasto compare the use of heparin and enoxaparin alone andalong with compression stockings in terms of incidence ofdeep vein thrombosis.Methodology: To do the research, 80 patients were randomlyassigned into 4 groups of heparin alone, heparinalong with stockings, enoxaparin alone, and enoxaparinalong with stockings (each contained 20 patients). In thefirst group, heparin at the dose of 5000 units per 12 hoursfor 3 days was used subcutaneously. In the second group,in addition to heparin, compression stockings were alsoutilized. In the third group underwent prophylaxis, enoxaparinat the dose of 40 mg per day for three days wasused subcutaneously. In the fourth group, in addition toenoxaparin, compression stockings were also used. Twoweeks after the completion of the medical and mechanicalprophylaxis, thrombosis was examined through Dopplerultrasonography. Data were analyzed using SPSS, version22, software and chi-square test (Fisher test) and ANOVA.Results: Only two cases of thrombosis (one case in thefirst group and one case in the third group) were observed.No case of thrombosis was seen in groups receivingcompression stockings along with medicine. Fisher’s exacttest indicated that there was no significant differenceamong four groups in terms of incidence of thrombosis.Conclusion: Adding compression stockings to heparin orenoxaparin had no significant effect on reducing the incidenceof deep vein thrombosis in patients with hysterectomy