Dental caries and hormonal changes in postmenopausal women
Keywords:
Dental caries, menopause, estrogen, cortisol, vitamin D.Abstract
Menopause is the period of life when occur physiological changes in women that give rise to adaptive changes at both systemic and oral levels. As we all begin to reach an older age, dental health and hygiene become a major concern. This study aimed to evaluate the relationship between hormonal and calcium levels during the postmenopausal period and dental caries (D.C). This study was composed of 35 postmenopausal women (PMW) (group1) (15 with dental caries (group1A) and 20 without dental caries (group1B), control group (group2) composed of 15 women with age under the menopause (premenopausal women). The study groups are free from chronic diseases like diabetes mellitus, cancers, and renal failure.
Serum was collected and calcium (Ca), vitamin D (Vit D), estrogen (Est), and cortisol (Cort) were analyzed. Our results show a significant decrease (P<0.05) in levels of serum calcium, vitamin D, and estrogen, and a significant increase (P<0.05) in levels of cortisol in PMW as compared with control. These differences are also present in PMW with dental caries as compared with PMW without dental caries. Conclusion: Dental caries is negatively related to serum calcium, vitamin D, and estrogen level while positively cortisol in postmenopausal women.
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