Osteoarthritis and obesity: the role of leptin in the knee joint

Authors

  • Patricia Jeaneth Carranco Herrera
  • Marcos Ali Palacio Rojas

Keywords:

osteoarthritis, obesity, adipose tissue, leptin.

Abstract

Osteoarthritis is a disease that is increasingly present in the population due to the pandemic of obesity, formerly attributed exclusively to obesity by weight load as the only factor that injured the joints, especially weight-bearing joints, This concept has been confirmed by research and evidence that weight gain alone is not an exclusive etiological factor, since the study of adipose tissue and its endocrine action, such as the production of leptin, has demonstrated its participation in the destruction of weight-bearing and non-weight-bearing joint structures.

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Published

2023-04-08

How to Cite

Carranco Herrera , P. J. ., & Palacio Rojas, M. A. . (2023). Osteoarthritis and obesity: the role of leptin in the knee joint. AVFT – Archivos Venezolanos De Farmacología Y Terapéutica, 41(4). Retrieved from http://saber.ucv.ve/ojs/index.php/rev_aavft/article/view/25997