Osteoarthritis and obesity: the role of leptin in the knee joint
Keywords:
osteoarthritis, obesity, adipose tissue, leptin.Abstract
Osteoarthritis is a disease that is increasingly present in the population due to the pandemic of obesity, formerly attributed exclusively to obesity by weight load as the only factor that injured the joints, especially weight-bearing joints, This concept has been confirmed by research and evidence that weight gain alone is not an exclusive etiological factor, since the study of adipose tissue and its endocrine action, such as the production of leptin, has demonstrated its participation in the destruction of weight-bearing and non-weight-bearing joint structures.
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