Adherence to prophylactic treatment of patients with haemophilia A and B using the VERITAS-Pro in a population on the Colombian Caribbean Coast

Authors

Keywords:

Haemophilia, VERITAS-Pro, Prophylaxis, Adherence, Colombian Caribbean Coast

Abstract

Background: Haemophilia is a disease that results in high costs worldwide, and whereby there is limited access to prophylactic treatment due to poor health conditions and difficultly in accessing healthcare; therefore, it becomes necessary to establish policies to improve the implementation or adherence of treatments in patients. Methods: An observational, cross-sectional, and prospective study was conducted, with the application of the VERITAS-Pro test, which was validated using Cronbach´s alpha. The adherence was determined using a scale-based on VERITAS-Pro. Previously, sociodemographic and clinical variables were collected in order to relate the data to a questionnaire. Results: 32 patients with haemophilia and prophylaxis treatment were included. They were divided into adults (>18 years-old) and minors (<18 years-old). The majority of participants evidenced haemophilia A (77.8% of adults and 64.3% of minors) and the majority of participants had severe haemophilia (77.8% of adults and 85.0% of minors). The internal consistency showed high reliability (α= 0.811 in minors and α= 0.858 in adults). The results showed that 66.7% of adults evidenced adherence while minors showed 50.0%. These results were compared with variables such as type of hemophilia, degree of hemophilia, presence of arthropathy, emergency admission, family history and inhibitors of coagulation factors. Conclusions: The VERITAS-Pro questionnaire showed high levels of consistency and reproducibility. The study population showed a high degree of adherence.  It was therefore useful to evaluate the adherence of haemophiliac patients in the Colombian Caribbean. 

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Published

2023-04-08

How to Cite

Alvíz Amador, A. ., Contreras Puentes, N. ., Gutiérrez Cuesta, J. ., Díaz Caballero, A. ., & Taron Dunoyer, A. . (2023). Adherence to prophylactic treatment of patients with haemophilia A and B using the VERITAS-Pro in a population on the Colombian Caribbean Coast. AVFT – Archivos Venezolanos De Farmacología Y Terapéutica, 41(4). Retrieved from http://saber.ucv.ve/ojs/index.php/rev_aavft/article/view/25994