Tumor del estroma gástrico (GIST). difícil obtención de biopsia por la vía endoscópica

Resumen

El 60 a 70% de los GIST ocurren en estómago, representando el 5% de los tumores gástricos. El diagnóstico preoperatorio es relativamente difícil dado que la toma de muestra es raramente obtenida durante la endoscopia. El tratamiento quirúrgico es el “gold standard” con una sobrevida a los 5 años del 50% en ausencia de metástasis, 20 meses en presencia de metástasis y de 9 a 12 meses en casos con enfermedad localmente recurrente. El imatanib en pacientes con metástasis o enfermedad irresecable produce respuesta en el 50% de los casos a los pocos meses.

Title
Gastrointestinal stromal tumors (GIST). Difficult biopsy by endoscopic means
Abstract
From 60 to 70% of G.I.S.T are located in the stomach, they represents about 5% of all gastric malignancies. Preoperative histologic diagnosis by endoscopic procedures is uncommon. Surgical treatment is considered the gold standard in these cases, with an overall 5 year survival of 50%, without metastasic disease, 20 months with it and 9 to 12 months when locally recurrent disease its present. The response observed with the use of Imatinib in patients with metastasic disease or not sensitive to surgical treatment can reach 50% with a few months of therapy.