Herpes Virus Simple tipo 2 ¿factor y/o cofactor en el cáncer del cuello uterino? Revisión narrativa de la literatura
Palavras-chave:
Herpes Virus Humano Tipo 2, Papilomavirus Humano, Carcinogénesis, Neoplasias del Cuello Uterino, Herpes Virus 2 Human, Human Papillomavirus, Carcinogenesis, Uterine Cervical NeoplasmsResumo
Revisar y analizar el posible papel del herpes virus simple tipo 2 como factor y/o cofactor en el origen y desarrollo del cáncer del cuello uterino Métodos: Se revisó la bibliografía latinoamericana e internacional, entre 1970 y junio de 2020. Términos de búsqueda: herpes virus simple tipo 2 y/o epidemiología, virus del papiloma humano y cáncer del cuello uterino.
Resultados: El herpes virus simple tipo 2 es considerado una de las infecciones de transmisión sexual más frecuentes en el mundo. Se ha relacionado con el origen y evolución de las neoplasias cervicales y sus precursores. Se analizan los posibles mecanismos por los que podría participar en la carcinogénesis del cáncer del cuello uterino, como cofactor con el papilomavirus o como factor independiente. Conclusiones: Se requieren más estudios clínicos, epidemiológicos, serológicos y moleculares para dilucidar la patogénesis del herpes virus simple tipo 2 en la carcinogénesis del cáncer cervical.
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