Assessment of right and left ventricular function by tissue Doppler image in young patients with hyperthyroidism

Resumen

Background: Hyperthyroidism is a thyroid hormone excess condition, and is the second most common thyroid dysfunction after hypothyroidism. Clinical symptoms associated with cardiovascular disorders differ between individuals and can include sinus tachycardia in both inactive and active formal and atrial arrhythmias, in specific atrial fibrillation in ageing persons with pre-existing heart disorders. Conventional Echo is a broadly presented procedure to identify subclinical heart failure in hyperthyroidism patients. Aim of study: to evaluate left and right function of ventricles in hyperthyroidism young patients used tissue Doppler appearance. Methods: A 45 case of hyperthyroidism and 45 healthy control with age more than 18 years and overt hyperthyroidism that confirmed by endocrinologist were included in this study that conducted between the first of March and the first of June of 2020. The Blood samples were drawn for all participants for Serum thyroid hormone levels measurement. The Echocardiography was performed with participants positioned at left lateral decubitus according to protocol of ASE guide lines with the use of GE Medical System Vivid nine ultrasound machine equipped with transducer a with frame rate 60-80 frame\sec. TDI imaging needs great frame rates (>100fps) for image acquirement with outstanding temporal determination. Result: Among echocardiographic parameters there were no significant differences in EF% between two groups (p=0.62), TDI examination for left ventricle shown that: S´, E/A and e´ were significantly decrease in cases than control participants, Tei index and E/e´ were significantly advanced in cases than control persons and a´ no any significant difference between normal persons and hyperthyroidism. TDI examination for right ventricle shown that: S´, E/A, e´ and E/e´ were no any significant difference between normal persons and hyperthyroidism, Tei index and a´ no any significant difference between normal persons and hyperthyroidism. Conclusions: Thyroid derangement especially hyperthyroidism, have a significant effect on cardiac functions. TDI measurements are useful, inexpensive, and easy to perform indices for detection of early LV and RV systolic and diastolic functional abnormalities in patients with hyperthyroidism.