Oxidative stress in preeclampsia, more than enzymes

Abstract

Preeclampsia is a disease characterized by increased blood pressure (blood pressure (BP) > 140 mmHg), proteinuria (300 mg/L/day) and edema, that occurs regularly after the twentieth week of gestation. There are risk factors such as chronic hypertension, diabetes mellitus and obesity to the development of this disease. Preeclampsia is pregnancyspecific, affecting 2% to 7% of women, and is a leading cause of perinatal and maternal morbidity and mortality. Preeclampsia has been associated with growth retardation, low birth weight and premature birth, mothers may have placental abruption, renal failure, cerebral hemorrhage, disseminated intravascular coagulation and circulatory collapse.