Evalution of liver function tests in patients with psoriasis

Abstract

Abnormal liver function tests are often seen in patients with Psoriasis (PS). This study was undertaken to examine the alanine aminotransferase (ALT; aspartate aminotransferase (AST), alkaline phosphatase (ALP), γ-glutamyltransferase (GGT), albumin) bilirubin in patients with Psoriasis.

Blood samples were collected from all patients with PS and healthy between 8 and 11 AM, after fasting overnight. ALT, ALP, GGT, albumin, bilirubin levels in each of the cases have been measured by spectrophotometric kit. There was a significant increase in serum ALT, ALP, GGT, while significant decreas in albumin, bilirubin levels in PS group when compared with healthy controls 

Conclusion: Liver abnormalities are common among PS patients and are associated with oxidative stress, more severe disease and certain therapies.