Tratamiento del infarto agudo al miocardio: nuevas perspectivas

Authors

  • Lessley Johanna Verdezoto Unaucho
  • Carlos Emilio Albarracín Revelo
  • Gissele Stephanie Verdezoto Unaucho
  • Clara De Lourdes Ramos Ávila
  • Gino Andrés Retamal Córdova
  • Andrés Enrique Pacheco Aguilar
  • Carlos Andrés Layedra Guayta
  • Paola Mishell Robalino López
  • Edison Santiago Riofrío Andaluz
  • Richard Fabricio Plasencia Lema

Abstract

Coronary artery disease is the leading cause of morbidity and mortality globally, with its most common form being acute myocardial infarction (AMI). The epidemiological impact of this entity is severe, promoting the development of new therapeutic alternatives to allow improved patient outcomes. Given the high prevalence of this condition and its growing pattern in recent decades, it has become a priority to work on strategies addressing aspects currently unattended by treatments, which at present focus on achieving prompt reperfusion and reducing the extension of the infarction. Nevertheless, new treatment lines indicate that it may be possible to prevent post-infarction cardiac remodeling by utilizing various types of stem cells, offering viable alternatives for patients who are not candidates for percutaneous coronary interventions. The objective of this review is to assess the new strategies for the treatment of AMI and the viability of their use in human models.

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Published

2023-02-13