Pruritus occurs in patients with chronic kidney disease: Features and associated factors

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Abstract

Introduction: Chronic kidney disease (CKD) discusses the kidneys being injured or the glomerular filtration rate less than 60mL/min / 1.73 m2 for more than three months.  The final stage of renal illness is the deadly stage of several CKDs, and its occurrence has increased obviously in the previous 30 years. The study aims to show the features of pruritus associated with CKD and its association with sociodemographic variables. Method: Cross-sectional study of 53 patients with chronic kidney disease collected from Baqubah dialysis center from period 1st of April 2020 to 1st of September 2020, inclusion criteria are all patients with chronic kidney disease suffer from rashes and pruritus while exclusion criteria are all patients suffer from rashes and pruritus not associate to CKD and cause by another disease. All patients take sociodemographic data like age, gender, sleep pattern, the severity of disease if not make patients quickly to sleep and location of pruritus. Results: CKD patients with pruritic with age 52 ± 6 years old 87% of all patients with age 45 years old and above and 13% below 45 years old. 23% of patients are females, and 77% are males, 40% of patients the pruritus interfere with their sleep while 60% do not. About 40% of patients with pruritic are severe, while 60% of them are not. 62% of pruritic patients occur in the trunk, while 38% occur in the entire body. There is a significant association between the severity of pruritus and gender. In addition, there is a significant association between the severity of pruritus and the affected area. As well as the gender and affected area, there is a significant association between severity of pruritus and sleep. Conclusion: Utmost communal symptom of skin in ESRD is pruritus, broadly identified as “uremic pruritus.” Due to there being no correct association with uremia, the critical association occurs more in males, age more than 45 years, interfere with sleep, and more in the trunk region.

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Published

2023-02-04