Gallbladder neoplasia as a preoperative diagnosis: case report and literature review

Authors

  • Vanessa Becerra Centro de Control de Cáncer Gastrointestinal “Dr. Luis E Anderson”. San Cristóbal, Estado Táchira – Venezuela.
  • Luz Lizcano Centro de Control de Cáncer Gastrointestinal “Dr. Luis E Anderson”. San Cristóbal, Estado Táchira – Venezuela.
  • Ángel Rivera Centro de Control de Cáncer Gastrointestinal “Dr. Luis E Anderson”. San Cristóbal, Estado Táchira – Venezuela.
  • Olga Silva Centro de Control de Cáncer Gastrointestinal “Dr. Luis E Anderson”. San Cristóbal, Estado Táchira – Venezuela.
  • Luz Carreño Centro de Control de Cáncer Gastrointestinal “Dr. Luis E Anderson”. San Cristóbal, Estado Táchira – Venezuela.
  • Denny Castro Centro de Control de Cáncer Gastrointestinal “Dr. Luis E Anderson”. San Cristóbal, Estado Táchira – Venezuela.

DOI:

https://doi.org/10.61155/2023.77.3.007

Keywords:

Gallbladder, adenocarcinoma

Abstract

Gallbladder cancer is the most common bile duct malignancy and shows striking variation between world regions. Its main form of diagnosis is incidental and by suspicion through imaging studies the less usual. Our case deals with a 51-year-old male patient, without comorbidities, who reports abdominal pain of 1 month of evolution, insidious onset, located in the right hypochondrium, oppressive, moderate intensity, non-radiating, associated with asthenia and adynamia. On physical examination, the abdomen was painful on deep palpation in the right hypochondrium, no masses were palpable, and no signs of peritoneal irritation. Ultrasound impresses an endoluminal lesion in the gallbladder and tomographically, endoluminal neoproliferative thickening is observed, with phase-contrasted enhancement; Therefore, he underwent surgery, performing exploratory laparotomy + radical cholecystectomy, whose histology concluded as well-differentiated adenocarcinoma of the gallbladder, being then referred to medical oncology to receive adjuvant treatment.

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References

Zaidi MY, Abou-Alfa GK, Ethun CG, Shrikhande SV, Goel M, Nervi B, Primrose J, Valle JW, Maithel SK. Evaluation and management of incidental gallbladder cancer. Chin Clin Oncol. 2019;8(4):37.

García P, Lamarca A, Díaz J, Carrera E, Roa JC, On Behalf Of The European-Latin American Escalon Consortium. Current and New Biomarkers for Early Detection, Prognostic Stratification, and Management of Gallbladder Cancer Patients. Cancers (Basel). 2020 7;12(12):3670.

Gupta P, Meghashyam K, Marodia Y, Gupta V, Basher R, Das CK, Yadav TD, Irrinki S, Nada R, Dutta U. Locally advanced gallbladder cancer: a review of the criteria and role of imaging. Abdom Radiol (NY). 2021;46(3):998-1007

Krell RW, Wei AC. Gallbladder cancer: surgical management. Chin Clin Oncol. 2019;8(4):36.

Qadan M, Kingham TP. Technical Aspects of Gallbladder Cancer Surgery. Surg Clin North Am. 2016; 96(2):229-45.

Okumura K, Gogna S, Gachabayov M, Felsenreich DM, McGuirk M, Rojas A, Quintero L, Seshadri R, Gu K, Dong XD. Gallbladder cancer: Historical treatment and new management options. World J Gastrointest Oncol. 2021; 13(10):1317-1335.

Cherkassky L, D'Angelica M. Gallbladder Cancer: Managing the Incidental Diagnosis. Surg Oncol Clin N Am. 2019; 28(4):619-630.

Song X, Hu Y, Li Y, Shao R, Liu F, Liu Y. Overview of current targeted therapy in gallbladder cancer. Signal Transduct Target Ther. 2020; 5(1):230.

Hickman L, Contreras C. Gallbladder Cancer: Diagnosis, Surgical Management, and Adjuvant Therapies. Surg Clin North Am. 2019; 99(2):337-355.

Kishi Y, Nara S, Esaki M, Hiraoka N, Shimada K. Extent of lymph node dissection in patients with gallbladder cancer. Br J Surg. 2018;105(12):1658-1664.

Zevallos Maldonado C, Ruiz Lopez MJ, Gonzalez Valverde FM, Alarcon Soldevilla F, Pastor Quirante F, Garcia Medina V. Ultrasound findings associated to gallbladder carcinoma. Cir Esp. 2014; 92(5):348-55.

Segura Grau A, Joleini S, Díaz Rodríguez N, Segura Cabral JM. Ecografía de la vesícula y la vía biliar [Ultrasound of gallbladder and bile duct]. Semergen. 2016;42(1):25-30. Spanish.

Sharma A, Sharma KL, Gupta A, Yadav A, Kumar A. Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update. World J Gastroenterol. 2017; 23(22):3978-3998.

Ethun CG, Postlewait LM, Le N, Pawlik TM, Buettner S, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Jin LX, Weber SM, Salem A, Martin RC, Scoggins C, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Merchant N, Cardona K, Maithel SK. A Novel Pathology-Based Preoperative Risk Score to Predict Locoregional Residual and Distant Disease and Survival for Incidental Gallbladder Cancer: A 10-Institution Study from the U.S. Extrahepatic Biliary Malignancy Consortium. Ann Surg Oncol. 2017;24(5):1343-1350.

Wernberg JA, Lucarelli DD. Gallbladder cancer. Surg Clin North Am. 2014;94(2):343-60.

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Published

2023-11-13

How to Cite

Becerra, V., Lizcano, L., Rivera, Ángel, Silva, O., Carreño, L., & Castro, D. (2023). Gallbladder neoplasia as a preoperative diagnosis: case report and literature review. Revista GEN, 77(3), 111–114. https://doi.org/10.61155/2023.77.3.007

Issue

Vol. 77 No. 3 (2023): July - September

Section

CLINICAL CASE

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