Gallbladder neoplasia as a preoperative diagnosis: case report and literature review
DOI:
https://doi.org/10.61155/2023.77.3.007Keywords:
Gallbladder, adenocarcinomaAbstract
Gallbladder cancer is the most common bile duct malignancy and shows striking variation between world regions. Its main form of diagnosis is incidental and by suspicion through imaging studies the less usual. Our case deals with a 51-year-old male patient, without comorbidities, who reports abdominal pain of 1 month of evolution, insidious onset, located in the right hypochondrium, oppressive, moderate intensity, non-radiating, associated with asthenia and adynamia. On physical examination, the abdomen was painful on deep palpation in the right hypochondrium, no masses were palpable, and no signs of peritoneal irritation. Ultrasound impresses an endoluminal lesion in the gallbladder and tomographically, endoluminal neoproliferative thickening is observed, with phase-contrasted enhancement; Therefore, he underwent surgery, performing exploratory laparotomy + radical cholecystectomy, whose histology concluded as well-differentiated adenocarcinoma of the gallbladder, being then referred to medical oncology to receive adjuvant treatment.
Downloads
References
Zaidi MY, Abou-Alfa GK, Ethun CG, Shrikhande SV, Goel M, Nervi B, Primrose J, Valle JW, Maithel SK. Evaluation and management of incidental gallbladder cancer. Chin Clin Oncol. 2019;8(4):37.
García P, Lamarca A, Díaz J, Carrera E, Roa JC, On Behalf Of The European-Latin American Escalon Consortium. Current and New Biomarkers for Early Detection, Prognostic Stratification, and Management of Gallbladder Cancer Patients. Cancers (Basel). 2020 7;12(12):3670.
Gupta P, Meghashyam K, Marodia Y, Gupta V, Basher R, Das CK, Yadav TD, Irrinki S, Nada R, Dutta U. Locally advanced gallbladder cancer: a review of the criteria and role of imaging. Abdom Radiol (NY). 2021;46(3):998-1007
Krell RW, Wei AC. Gallbladder cancer: surgical management. Chin Clin Oncol. 2019;8(4):36.
Qadan M, Kingham TP. Technical Aspects of Gallbladder Cancer Surgery. Surg Clin North Am. 2016; 96(2):229-45.
Okumura K, Gogna S, Gachabayov M, Felsenreich DM, McGuirk M, Rojas A, Quintero L, Seshadri R, Gu K, Dong XD. Gallbladder cancer: Historical treatment and new management options. World J Gastrointest Oncol. 2021; 13(10):1317-1335.
Cherkassky L, D'Angelica M. Gallbladder Cancer: Managing the Incidental Diagnosis. Surg Oncol Clin N Am. 2019; 28(4):619-630.
Song X, Hu Y, Li Y, Shao R, Liu F, Liu Y. Overview of current targeted therapy in gallbladder cancer. Signal Transduct Target Ther. 2020; 5(1):230.
Hickman L, Contreras C. Gallbladder Cancer: Diagnosis, Surgical Management, and Adjuvant Therapies. Surg Clin North Am. 2019; 99(2):337-355.
Kishi Y, Nara S, Esaki M, Hiraoka N, Shimada K. Extent of lymph node dissection in patients with gallbladder cancer. Br J Surg. 2018;105(12):1658-1664.
Zevallos Maldonado C, Ruiz Lopez MJ, Gonzalez Valverde FM, Alarcon Soldevilla F, Pastor Quirante F, Garcia Medina V. Ultrasound findings associated to gallbladder carcinoma. Cir Esp. 2014; 92(5):348-55.
Segura Grau A, Joleini S, Díaz Rodríguez N, Segura Cabral JM. Ecografía de la vesícula y la vía biliar [Ultrasound of gallbladder and bile duct]. Semergen. 2016;42(1):25-30. Spanish.
Sharma A, Sharma KL, Gupta A, Yadav A, Kumar A. Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update. World J Gastroenterol. 2017; 23(22):3978-3998.
Ethun CG, Postlewait LM, Le N, Pawlik TM, Buettner S, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Jin LX, Weber SM, Salem A, Martin RC, Scoggins C, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Merchant N, Cardona K, Maithel SK. A Novel Pathology-Based Preoperative Risk Score to Predict Locoregional Residual and Distant Disease and Survival for Incidental Gallbladder Cancer: A 10-Institution Study from the U.S. Extrahepatic Biliary Malignancy Consortium. Ann Surg Oncol. 2017;24(5):1343-1350.
Wernberg JA, Lucarelli DD. Gallbladder cancer. Surg Clin North Am. 2014;94(2):343-60.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.
Usted es libre de:
- Compartir — copiar y redistribuir el material en cualquier medio o formato
- Adaptar — remezclar, transformar y construir a partir del material
- para cualquier propósito, incluso comercialmente.
Bajo los siguientes términos:
-
Atribución — Usted debe dar crédito de manera adecuada, brindar un enlace a la licencia, e indicar si se han realizado cambios. Puede hacerlo en cualquier forma razonable, pero no de forma tal que sugiera que usted o su uso tienen el apoyo de la licenciante.
- No hay restricciones adicionales — No puede aplicar términos legales ni medidas tecnológicas que restrinjan legalmente a otras a hacer cualquier uso permitido por la licencia.