Cutaneous metastasis of adenocarcinoma of the cecum: report of a case and review of the literature
DOI:
https://doi.org/10.61155/2023.77.2.004Keywords:
Metastasic, skin, adenocarcina, cecumAbstract
Metastatic skin tumors are rare, with an incidence of less than 10% and a colorectal adenocarcinoma origin of less than 6%. The present case consists of a 74 year old female patient, controlled type 2 diabetic, who reports 07 months of evolution, abdominal pain, located in the hypochondrium and right flank, of moderate intensity, not irradiated; associated with changes in the evacuation pattern and weight loss. Physical examination reveals a plaque type lesion in the cranial region, left parietal, with a nodular surface, painless, whose biopsy reports poorly differentiated metastatic adenocarcinoma, and colonoscopy reveals a raised lesion with a smooth and erythematous surface at the level of the cecum; histologically it is identified as a poorly differentiated adenocarcinoma with signet ring cells; This last finding is also unusual, since only 0.1-2.4% of primary signet ring cell carcinomas occur in the colon. The patient is referred to medical oncology; however, she died before starting palliative treatment.
Downloads
References
Yang Y, Chen R, Zhang R. Cutaneous metastasis of a colon adenocarcinoma presenting as an unusual manifestation: a report of one case. Int J Clin Exp Pathol. 2020;13(7):1897-1901.
Nesseris I, Tsamakis C, Gregoriou S, Ditsos I, Christofidou E, Rigopoulos D. Cutaneous metastasis of colon adenocarcinoma: case report and review of the literature. An Bras Dermatol. 2013;88(6 Suppl 1):56-8. doi: 10.1590/abd1806-4841.20132441
Kemal Y, Odabaşı EA, Kemal Ö, Bakırtaş M. Cutaneous metastasis of colon adenocarcinoma. Turk J Surg. 2018;34(3):237-239. doi: 10.5152/turkjsurg.2017.3298
Faenza M, Del Torto G, Di Costanzo P, Pieretti G, Lamberti R, Franco R, Ferraro GA, Nicoletti GF. Large single cutaneous metastasis of colon adenocarcinoma mimicking a squamous cell carcinoma of the skin: A case report. Int J Surg Case Rep. 2019; 56:96-100. doi: 10.1016/j.ijscr.2019.02.043
Fyrmpas G, Barbetakis N, Efstathiou A, Konstantinidis I, Tsilikas C. Cutaneous metastasis to the face from colon adenocarcinoma. Case report. Int Semin Surg Oncol. 2006;3:2. doi: 10.1186/1477-7800-3-2
Yunoki K, Yano T, Yoshimitsu M, Oshita K, Kubota T, Ishida M, Satoh D, Choda Y, Nakano K, Shirakawa Y, Matsukawa H, Idani H, Shiozaki S, Okajima M. Cutaneous metastasis of cecum cancer with MSI-high and BRAFV600E mutation: a case report. Surg Case Rep. 2021;7(1):185. doi: 10.1186/s40792-021-01265-w
Liao L, Cheng Q, Zhu G, Pei F, Ye S. Cutaneous metastasis of ascending colon cancer harboring a BRAF V600E mutation: A rare case report. Medicine (Baltimore). 2020;99(21):e20026. doi: 10.1097/MD.0000000000020026
Bittencourt MJS, Imbiriba AA, Oliveira OA, Santos JEBD. Cutaneous metastasis of colorectal cancer. An Bras Dermatol. 2018;93(6):884-886. doi: 10.1590/abd1806-4841.20187610
Ahmed G, Velasco SA, Van Doren L, Saif MW. First Case of Topical 5-FU Therapy for Cutaneous Metastasis in a Patient with Colon Cancer. Eurasian J Med Oncol. 2020;4(1):89-93. doi: 10.14744/ejmo.2020.81980
Nambiar S, Karippot A. Multiple Cutaneous Metastases as Initial Presentation in Advanced Colon Cancer. Case Rep Gastrointest Med. 2018; 2018:8032905. doi: 10.1155/2018/8032905
Fong SH, Narasimha N, Thakkar R, Misra S, Thakkar D. A rare isolated cutaneous metastatic mass after colon cancer resection. J Surg Case Rep. 2021;2021(12): rjab571. doi: 10.1093/jscr/rjab571
Correia P, Correia JF, Scigliano H, Nora M. Unusual Cutaneous Metastases From Colon Adenocarcinoma. Cureus. 2021;13(3): e14065. doi: 10.7759/cureus.14065
Strickley JD, Jenson AB, Jung JY. Cutaneous Metastasis. Hematol Oncol Clin North Am. 2019;33(1):173-197. doi: 10.1016/j.hoc.2018.08.008
Mora-Guzmán I, Di Martino M, Muñoz de Nova JL, Viamontes Ugalde FE, Rodríguez Sánchez A. Primary signet ring cell carcinoma of the colon: A rare condition with a poor prognosis. A report on two cases. Rev Gastroenterol Mex (Engl Ed). 2018;83(3):358-360. English, Spanish. doi: 10.1016/j.rgmx.2017.03.003
Sasaki S, Masaki T, Umetani N, Futakawa N, Ando H, Muto T. Characteristics in primary signet-ring cell carcinoma of the colorectum, from clinicopathological observations. Jpn J Clin Oncol. 1998;28(3):202-6. doi: 10.1093/jjco/28.3.202
Nitsche U, Zimmermann A, Späth C, Müller T, Maak M, Schuster T, Slotta-Huspenina J, Käser SA, Michalski CW, Janssen KP, Friess H, Rosenberg R, Bader FG. Mucinous and signet-ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis. Ann Surg. 2013;258(5):775-82; discussion 782-3. doi: 10.1097/SLA.0b013e3182a69f7e.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.
Usted es libre de:
- Compartir — copiar y redistribuir el material en cualquier medio o formato
- Adaptar — remezclar, transformar y construir a partir del material
- para cualquier propósito, incluso comercialmente.
Bajo los siguientes términos:
-
Atribución — Usted debe dar crédito de manera adecuada, brindar un enlace a la licencia, e indicar si se han realizado cambios. Puede hacerlo en cualquier forma razonable, pero no de forma tal que sugiera que usted o su uso tienen el apoyo de la licenciante.
- No hay restricciones adicionales — No puede aplicar términos legales ni medidas tecnológicas que restrinjan legalmente a otras a hacer cualquier uso permitido por la licencia.