Vesicular motility in patients with hepatic cirrhosis with and without vesicular lithiasis

Authors

  • Silvana Sarabia Boada Hospital Universitario de Caracas. Caracas, Venezuela.
  • Cesar Edesio Louis Hospital Universitario de Caracas. Caracas, Venezuela.

DOI:

https://doi.org/10.61155/2023.77.2.002

Keywords:

cirrhosis, lithiasis, functional ultrasonography, gallbladder motility, RUSF®

Abstract

Background: Liver cirrhosis is associated with the risk of gallstones whose lithogenesis is not well established. Objective: To evaluate gallbladder motility in patients with liver cirrhosis with and without gallstones who attended the Ultrasound Unit of the Gastroenterology Service of the Autonomous Institute Hospital Universitario de Caracas between June and November 2019. Methodology: Prospective, cross-sectional and descriptive study. Of 300 cirrhotic patients, 32 met the inclusion criteria. They were classified into 2 groups: with and without lithiasis, determining fasting gallbladder volume and after intake of RUSF® (hypercaloric nutritional supplement), residual volume and gallbladder ejection fraction. Mean was calculated and quantitative Gaussian variables were compared using Student's T test, Mann Whitney test for non-Gaussian variables and Chi square for qualitative variables, considering significant a value of p ≤ 0.05. Results: 20 had lithiasis and 12 did not, the average age was 56.063 ± 12.24 years, male gender (68.75%) and alcoholic etiology (62%) predominated. When comparing motility variables between groups, there were statistically significant differences in fasting gallbladder volume (35.47 vs. 18.42, p=0.0001), volume at 18 minutes (29.42 vs. 16.95, p=0.0017) and residual volume (13.03 vs. 4.22, p=0.0001). Conclusion: Cirrhotic patients with gallstones have greater compromise of gallbladder motility that could be conditioned by the presence of stones.

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Published

2023-08-26

How to Cite

Sarabia Boada, S., & Louis, C. E. (2023). Vesicular motility in patients with hepatic cirrhosis with and without vesicular lithiasis. Revista GEN, 77(2), 50–56. https://doi.org/10.61155/2023.77.2.002

Issue

Vol. 77 No. 2 (2023): April - June

Section

ORIGINAL ARTICLE

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