Nevu agminado en síndrome de nevus displásico

Mayerith Torreyes-Reyes; Nathalie Lascano; Juan Barzallo; Lizeth Lafuente

Authors

Mayerith Torreyes-Reyes Skinlaser Center, Quito,
Nathalie Lascano Hospital Vozandes Quito/Universidad UTE. Quito,
Juan Barzallo Skinlaser Center, Quito,
Lizeth Lafuente Postgrado de Dermatología de segundo año de la Universidad UTE. Quito,

Keywords:

Agminated Nevus Syndrome, Dysplastic Nevus, Agminated Nevi.

Abstract

Agminate melanocytic nevus (AMN) are little reported in the world literature. The agminated nevus (NA) can have various origins, depending on it, they can develop dysplastic characteristics, with a potential risk of developing melanoma and become part of Dysplastic Nevus Syndrome (SND) according to its clinical, dermoscopic, histological and history diagnosis. family. The objective of this work is to present and discuss the clinical case of a 26-year-old male patient with no pathological history, evaluated at the Clinica Dermatologica Skinlaser in Quito Ecuador in May 2020, who presented multiple nevi on the body surface, especially in the back at posterior and interscapular level. The study emphasizes the importance of dermoscopic controls and follow-up are essential to recognize signs of atypia and changes that lead to suspicion of malignancy.

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References

Barnhill R, Piepkorn M, Busam K. Pathology of Melanocytic Nevi and Melanoma. Third. Springer; 2014.

LeBoit P, Burg G, International Agency for Research on Cancer, World Health Organization, International Academy of Pathology, European Organization for Research on Treatment of Cancer, Universitäts Spital Zürich Departement Pathologie. Melanocytic tumors. In: Pathology and Genetics of Skin Tumors. Lyon (France): IARC Press; 2006:50.

Diluvio L, Mazzeo M, Bianchi L, Campione E. Agminated Dermal Melanocytosis in the Territory of Ota's Nevus. Actas Dermo-Sifiliográficas (English Edition). 2018 september, Issue 7; 109: 653-655

Carreño-Gayosso EA, Mitre-Solórzano GR, Rodríguez-Mena A, Hernández-Torres MM, Ramírez-Godínez JB. Nevu melanocítico adquirido y agminado. Dermatol Rev Mex. 2018;62(2):151-156.

Choi YJ, Kim HS, Lee JY, Kim HO, Park YM. Agminated acquired melanocytic nevi of the common and dysplastic type. Ann Dermatol. 2013 Aug; 25(3): 380–382. DOI: 10.5021/ad.2013.25.3.380

Happle R. The categories of cutaneous mosaicism: a proposed classification. Am J Med Genet Part A 2016;170A:452- 459. DOI: 10.1002/ajmg.a.37439.

Shimasaki Y, Fukuta Y, Yoshida Y, Higaki-Mori H, Yamamoto O. Acquired agminated melanocytic naevi: Report of two cases and review of the literature. Acta Dermato-Venereologica. 2012; 92:603-4.

Carreno-Gayosso EA, Hernández-Peralta SL, Guevara-Gutiérrez E, Solis-Ledezma G. Guillermo. Agminated atypical melanocytic nevus associated with Langerhans cell histiocytosis. An. Bras. Dermatol. [online]. 2019; 94 (4): 455-457. Epub Oct 17, 2019. https://doi.org/10.1590/abd1806-4841.20198620.

Hypólito Silva J, Costa Soares de Sá B, Ribeiro de Ávila ALR, Landman G, Duprat Neto JP. Atypical mole syndrome and dysplastic nevi: Identification of populations at risk for developing melanoma - review article [Internet]. [cited 2020 Jul 8]. Clinics. Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo; 2011; 66 (3):493–9. doi: 10.1590/s1807-59322011000300023.

Rosendahl CO, Grant-Kels JM, Que SK. Dysplastic nevus: Fact and fiction. J Am Acad Dermatol. 2015;73(3):507-512. DOI: 10.1016/j.jaad.2015.04.029

Cabrera HN, Mohr Y, Núñez L. Síndrome del nevu atípico displásico familiar con síndrome Li-Fraumeni símil. Dermatol. Argent. 2019; 25 (1): 21-24. Disponible en: https://test.dermatolarg.org.ar/index.php/dermatolarg/issue/view/138

Gandini S, Sera F, Cattaruzza MS, Pasquini P, Abeni D, Boyle P, et al. Meta-analysis of risk factors for cutaneous melanoma: I.Common and atypical naevi. Eur J Cancer. 2005; 41(1):28-44. PMID: 15617989.

Suh KS, Park JB, Kim JH, Seong SH, Jang JY, Hyeon M, et al. Dysplastic nevus: Clinical features and usefulness of dermoscopy. J Dermatol. 2019;46(2): e76-e77. DOI:10.1111/1346-8138.14583

Vidal-Flores AA, Morales-Sánchez MA, Peralta-Pedrero ML, Jurado-Santa Cruz F. Exactitud diagnóstica de la dermatoscopia para diferenciar entre nevu atípico y nevu común Rev Cent Dermatol Pascua. Sep-Dic 2018; 27(3)

LeBoit PE, Burg G, Weedon D, Sarasain A (eds.). Pathology and genetics of skin tumors. World Health Organization. Classification of Tumors. IARRC Press: Lyon 2006.

Clarke LE. Dysplastic nevi. Clin Lab Med. 2011; 31: 255–265. DOI: 10.1016/j.cll.2011.03.003

Duffy K, Grossman D. The dysplastic nevus: From historical perspective to management in the modern era. Part II. Molecular aspects and clinical management. J Am Acad Dermatol. 2012; 67(1): 19e1-19e12.

Mariano da Rocha CR, Corsetti Grazziotin T, Widholzer Rey MC, Luzzatto L, Rangel Bonamigo R. Congenital agminated melanocytic nevus - Case report. An Bras Dermatol. 2013;88 (6 Suppl 1):170-2. DOI: http://dx.doi.org/10.1590/abd1806-4841.20132137

Pérez Vásquez C, Paredes Arcos A, Sánchez-Félix G, Carbajal-Chávez T. Nevus azul agminado: reporte de caso. Comunicación breve. Dermatol Peru. 2017; 27 (1)

Cervigón González I, Palomo Arellano A, Torres Iglesias LM, Serrano Egea A, Moreno Gómez E, Palomero Domínguez MA. Nevus agminados de Spitz. Anales de Pediatría (junio 2012); 76(6): 373-374 . DOI: 10.1016/j.anpedi.2011.02.020

Mosquera T, Marini MA, Saponaro AE. Fotografía corporal total y dermatoscopia: su valor en la detección precoz de melanoma. Fronteras en Medicina. 2015: 10(2).