Heart failure: challenges in pharmacological therapy

Authors

  • Galo Juvenal Vinueza Aguay Universidad Técnica de Ambato, Hospital General Docente Ambato – Tungurahua, Ecuador
  • Anthony Ricardo Chiluisa Mancheno Pregrado-Medicina. Universidad Técnica de Ambato – Tungurahua, Ecuador
  • Christian Natanael Aveiga Flores Pregrado –Medicina. Universidad Técnica de Ambato – Tungurahua, Ecuador

Keywords:

Heart failure, drug treatment, therapeutic advances, quality of life.

Abstract

Introduction: Heart Failure (HF) is a clinical entity of great importance, due to its high incidence and mortality, therefore the concern of conducting constant and updated reviews to optimize their treatment and thus impact the morbidity and mortality of patients. Objective: to critically analyze the medical literature, in the pharmacological treatment of heart failure to offer a better quality of life to the patient. Methods: documentary research through the systematic review of primary articles in scientific journals in bibliographic databases in health sciences: Pub Med, Google Scholar, Elsevier, ScienceDirect, Virtual Health Library (VHL) PAHO and Scielo, among the years of 2014 and 2018, for this the following descriptors were determined: heart failure, treatment, challenges, quality of life. 28 updated and collated digital articles were reviewed. Results: In the current treatment of heart failure, the Sacubitril / Valsartan combination prevails, since it reduces the risk of cardiovascular death by 20% and hospitalization by 21%; In addition, it reduces adverse effects in relation to conventional treatment with (ACEI). Conclusion: the new pharmacological therapies in heart failure, allow to replace conventional therapies and optimizing quality of life.

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How to Cite

Vinueza Aguay, G. J., Chiluisa Mancheno, A. R., & Aveiga Flores, C. N. (2019). Heart failure: challenges in pharmacological therapy. Revista Digital De Postgrado, 8(3), e181. Retrieved from http://saber.ucv.ve/ojs/index.php/rev_dp/article/view/17078