DETECCION DE Mycobacterium tuberculosis POR MÉTODOS MICROBIOLOGICOS CONVENCIONALES Y CARACTERISTICAS DEL PERIODONTO DE UN GRUPO DE PACIENTES CON TUBERCULOSIS
Keywords:
Mycobacterium tuberculosis, Baciloscopía, cavidad bucal, Bacilloscopy, oral cavitiesAbstract
Objetivo: establecer la importancia del diagnóstico microbiológico de la Tuberculosis.Metodología: 15 pacientes que asistieron al servicio del Hospital Simón Bolívar, Caracas Venezuela, con cuadro clínico presuntivo de Tuberculosis pulmonar fueron estudiados a través del examen en cavidad bucal, radiografía de tórax, Baciloscopía (BK) y método de Petroff, tomando en consideración los signos y síntomas de cada uno de ellos.
Resultados: 11 de las 15 muestras de esputo fueron BK (+) y 4 BK (-). Mycobacterium tuberculosis se aisló en 7 de las muestras incluyendo los pacientes que presentaron BK (-). Desde el punto de vista radiográfico, 10 pacientes presentaron lesión bilateral, 4 lesión unilateral y 1 fibrotorax. El examen en cavidad bucal permitió observar enfermedad periodontal de leve a moderada en 14 de los pacientes, 8 de ellos de manera localizada y 6 de manera generalizada.
La detección de M. tuberculosis a través del BK sigue siendo un método de importancia para establecer en conjunto con los antecedentes, epidemiología, clínica, radiografía, serología e histopatología del paciente el diagnóstico definitivo de la tuberculosis, sin embargo, la técnica de PCR puede complementar dicho estudio.
Palabras clave: Mycobacterium tuberculosis, Baciloscopía, cavidad bucal.
Abstract.
Mycobacterium tuberculosis, aethiological agent of tuberculosis is a curved, aerobic, non sporulated and non motile rod that is a resistant aganaist dissecation effects. 15 patients were selected in this study who assited to Neumonology service located at Simón Bolívar Hospital, Caracas, Venezuela. These patients who had presuntive lung tuberculosis were studied considering their sings and simthomps. Oral cavities of each patient were studied considering their sings and sinthomps. Oral cavities of each patient were examinated and thorax Rx, Bacilloscopy (BK) and Petroff method were taked from each one in order to detect this rod. Our findings related that 11 out of 15 sputum samples were BK (+) and the other 4 were BK (-). M. tuberculosis was isolated in 7 samples, including BK (-) patients. Radiografically, 10 patients presented bilateral lesion, 4 presented unilateral lesion and 1 fibrothorax. Examination of oral cavities showed that 8 patients presented localizated periodontal disease and 6 presented generalizated periodontal disease.
Detection of M. tuberculosis using BK continue to be an important method for identification of this bacteria, considering also epidemiological, clinical, radiographical, serological and histopathological studies in order to establish definitive diagnosis of TBC. Aditionally, Polimerase Chain Reaction (PCR) is an excellent method used to complement identification studies of this microorganism.
Key words: Mycobacterium tuberculosis, Bacilloscopy, oral cavities.
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Published
2011-05-26
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