|
|
SABER UCV >
Buscar por Autor Benaim, G
Mostrando resultados 7 a 24 de 24
| Fecha de publicación | Título | Autor(es) | | 2020 | Determination of intracellular Ca2+ concentration on the human pathogens trypanosomatids Leishmania mexicana and Trypanosoma cruzi by the use of the fluorescent Ca2+ indicator Fura-2. Bioprotocols. 10(18): e3766. DOI:10.21769/BioProtoc.3766 | Rey-Cibati, A; Valladares-Delgado, M; Benaim, G |
| 2020 | Disruption of intracellular calcium homeostasis as a therapeutic target against Trypanosoma cruzi. Frontiers Cell. Infect. Microbiol.10: 46. doi: 10.3389/fcimb.2020.00046 | Benaim, G; Paniz-Mondolfi, A; Sordillo, E.M; Martinez-Sotillo, N |
| 2014 | Dronedarone, an Amiodarone Analog with an Improved Anti-Leishmania mexicana Efficacy. Antimicrob. Agents Chemother 58: 2295-2303 | Benaim, G; Casanova, P; Hernandez-Rodriguez, V; Mujica-Gonzalez, S; Parra-Gimenez, N; Plaza-Rojas, L; Concepcion, J.L; Liu, Y.L; Oldfield, E; Paniz-Mondolfi, A; Suarez, A |
| 2016 | Drug repositioning for neglected tropical protozoan diseases. Curr. Top. Med. Chem. 16: 2201-2222 | Sbaraglini, M.L; Vanrell, M.C; Bellera, C.L; Benaim, G; Carrillo, C; Talevi, A; Romano, P.S |
| 2021 | Editorial: Advances in the Molecular Biology of Trypanosomatid Pathogens: New Strategies Against Ancient Enemies. Front. Cell. Infect. Microbiol. 11:777008.doi: 10.3389/fcimb.2021.777008 | Benaim, G; Paniz-Mondolfi, A.E; Ramírez, J.D; Sordillo, E.M |
| 2002 | Efecto del etanol y del fosfatidiletanol sobre la Ca2+-ATPasa de la membrana plasmática "in situ". Arch. Venezol. Farmacol. Terap. 21: 83-90 | Cervino, V; Benaim, G |
| 2017 | Efecto de un metilen-dioxiflavonoide aislado de Iresine diffusa sobre la viabilidad celular de Leishmania mexicana y la homeostasis intracelular del Ca2+. Invest. Clín. 58: 334-351. | De Gouveia, Y; Hernández-Rodríguez, V; Rodríguez-Durán, J; Suárez, A; Benaim, G |
| 2022 | Effect of Tetrahydroquinoline Derivatives on the Intracellular Ca2+ Homeostasis in Breast Cancer Cells (MCF-7) and its Relationship with Apoptosis. Invest. Clin. 63: 243-261 | Maksoud, S; Mayora, A; Colman, L; Sojo, F; Pimentel, A.A; Kouznetsov, V; Merchán-Arenas, D; Romero, A.H; Arvelo, F; De Sanctis, J.B; Benaim, G |
| 2019 | Identification and Electrophysiological Properties of a Sphingosine-dependent Plasma Membrane Ca2+ Channel in Trypanosoma cruzi. FEBS J. 286: 3909-3925. doi: 10.1111/febs.14947 | Rodriguez-Duran, J; Pinto-Martinez, A; Castillo, C; Benaim, G |
| 2016 | Inhibition of Leishmania mexicana Growth by the Tuberculosis Drug SQ109. Antimicrob Agents Chemother. 60: 6386-6389 | García-García, V; Oldfield, E; Benaim, G |
| 2004 | La Ca2+-ATPasa de la membrana plasmática como enzima clave en la homeostasis intracelular del calcio. Estimulación por etanol y otros efectores. (Revisión). Acta Cient. Venezol. 55: 304-314 | Benaim, G |
| 2018 | Mechanism of Action of Miltefosine on Leishmania donovani Involves the Impairment of Acidocalcisome Function and the Activation of the Sphingosine-Dependent Plasma Membrane Ca2+ Channel. Antimicrob Agents Chemother. 62: 1-10 | Pinto-Martinez, A; Rodriguez-Durán, J; Serrano-Martin, X; Hernandez-Rodriguez, V; Benaim, G |
| 2002 | Phosphorylation of Calmodulin: Functional Implications. (Review). Eur. J. Biochem. 269: 3619-3631 | Benaim, G; Villalobo, A |
| 2015 | SQ109: A New Drug Lead for Chagas Disease. Antimicrob Agents Chemother. 59: 50-61 | Veiga-Santos, P; Li, K; Lameira, L; de Carvalho, T.H; Huang, G; Galizzi, M; Shang, N; Li, Q; Gonzalez-Pacanowska, D; Hernandez-Rodriguez, V; Benaim, G; Guo, R.T; Urbina, J.A; Docampo, R; de Souza, W; Oldfield, E |
| 2023 | Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino) ethyl Benzoate Derivatives. Pharmaceuticals 2023, 16, 1709 | Gutiérrez, J.E; Ramírez, H; Fernandez-Moreira, E; Acosta, M.E; Mijares, M.R; De Sanctis, J.B; Gurská, S; Džubák, P; Hajdúch, M; Labrador-Fagúndez, L; Stella, B.G; Diaz-Perez, L; Benaim, G; Charris, J.E |
| 2016 | Synthesis of Ergosterone-coupled Triazol and characterization of their biological activity on Leishmania mexicana promastigotes: Induction of mitochondrial dysfunction, oxidative stress, and acidocalcisomes Ca2+ release. Microbial Cell. 3: 14-28 | Figarella, K; Marsiccobetre, S; Arocha, I; Colina, W; Hasegawa, M; Rodriguez, M; Duszenko, M; Benaim, G; Uzcategui, N.L |
| 2024 | Unmasking the mechanism behind Miltefosine: Revealing the disruption of intracellular Ca2+ homeostasis as a rational therapeutic target in leishmaniasis and Chagas disease. Biomolecules 2024, 14, 406. | Benaim, G; Paniz-Mondolfi, A |
| 2019 | Venezuela’s humanitarian crisis, resurgence of vector-borne diseases and implications for spillover in the region: a call for action. Lancet Infect. Dis. 3099: 30757-30756. | Grillet, M.E; Hernández, J.V; Llewellyn, M; Paniz-Mondolfi, A; Tami, A; Vincenti, F; Marquez, M; Mogollon-Mendoza, A; Hernandez-Pereira, C; Plaza-Morr, J; Blohm, G; Grijalva, M; Costales, J.A; Fergusson, H; Schwabl, P; Castro, L.H; Lamberton, P; Streiker, D; Haydon, D; Miles, M.A; Segovia, M; Acosta-Serrano, A; Acquattelam, H; Basáñez, M.G; Benaim, G; Conn, J.E; Freilij, H; Hotez, P; Kato, H; Lednicky, J; Mas-Coma, S; Morris, J.E; Navarro, J.C; Urbina, J.A; Villegas, L; Martinez, C.E; Rodríguez, M; Carrasco, H; Crainey, L; Luz, S; Moreno, J; Noya, O; Ramírez, J.D; Alarcón-de Noya, B |
Mostrando resultados 7 a 24 de 24
|
